Surgical aortic valve replacement with new-generation bioprostheses: Sutureless versus rapid-deployment

Massimo Massetti, Ginevra Federica D'Onofrio, Giovanni Troise, Daniele Maselli, Augusto D'Onofrio, Stefano Salizzoni, Claudia Filippini, Chiara Tessari, Lorenzo Bagozzi, Antonio Messina, Margerita Dalla Tomba, Manfredo Rambaldini, Magnus Dalén, Francesco Alamanni, Carmelo Mignosa, Claudio Russo, Loris Salvador, Roberto Di Bartolomeo, Ruggero De Paulis, Ottavio AlfieriCarlo Maria De Filippo, Michele Portoghese, Uberto Bortolotti, Mauro Rinaldi, Gino Gerosa

Risultato della ricerca: Contributo in rivistaArticolo in rivista

7 Citazioni (Scopus)

Abstract

Objectives: The aim of this retrospective multicenter study was to compare early clinical and hemodynamic outcomes of Perceval-S sutureless (Livanova, London, United Kingdom) and Intuity rapid-deployment (Edwards Lifesciences, Irvine, Calif) bioprostheses. Methods: Data from patients who underwent isolated or combined aortic valve replacement with Perceval-S and with Intuity bioprostheses at 18 cardiac surgical institutions were analyzed. Propensity matching was performed to identify similar patient cohorts. Results: We included 911 patients from March 2011 until May 2017. Perceval-S and Intuity valves were implanted in 349 (38.3%) and in 562 (61.7%) patients, respectively. Propensity score identified 117 matched pairs. In the matched cohort, device success was 99.1% and 100% in Perceval-S and Intuity group, respectively (P = 1.000). Thirty-day Valve Academic Research Consortium mortality occurred in 2 (1.7%) and 4 (3.4%) patients in the Perceval-S and in Intuity group, respectively (P = .6834). The rate of postoperative new permanent pacemaker implantation was 6% (7 patients) and 6.8% (8 patients) in the Perceval-S and in Intuity group, respectively (P = .7896). Perceval-S valve implantation requires significantly shorter aortic crossclamp and cardiopulmonary bypass times than Intuity valve implantation (aortic crossclamp time for isolated, 52 ± 14 minutes vs 62 ± 24 minutes; P < .0001). Peak transaortic gradients were 22.4 ± 8.1 mm Hg and 19.6 ± 6.7 mm Hg (P = .0144), whereas mean gradients were 11.8 ± 4.7 mm Hg and 10.5 ± 3.9 mm Hg (P = .0388) in the Perceval-S and Intuity groups, respectively. Conclusions: Sutureless Perceval-S and rapid-deployment Intuity bioprostheses provide good and similar early clinical and hemodynamic outcomes. Perceval-S valve implantation requires shorter crossclamp and cardiopulmonary bypass times, whereas Intuity valve implantation provides lower transaortic peak and mean gradients.
Lingua originaleEnglish
pagine (da-a)432-442
Numero di pagine11
RivistaJOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
Volume159
DOI
Stato di pubblicazionePubblicato - 2020

Keywords

  • aortic valve
  • rapid deployment aortic bioprosthesis
  • replacement
  • sutureless aortic bioprosthesis

Fingerprint Entra nei temi di ricerca di 'Surgical aortic valve replacement with new-generation bioprostheses: Sutureless versus rapid-deployment'. Insieme formano una fingerprint unica.

Cita questo