Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort

Andrea De Luca, István Bartha, Matthias Assel, Peter M.A. Sloot, Maurizio Zazzi, Carlo Torti, Eugen Schülter, Anders Sönnerborg, Ana B. Abecasis, Kristel Van Laethem, Andrea Rosi, Jenny Svärd, Roger Paredes, David A.M.C. Van De Vijver, Anne-Mieke Vandamme, Viktor Müller

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

4 Citazioni (Scopus)

Abstract

Superinfection with drug resistant HIV strains could potentially contribute to compromised therapy in patients initially infected with drug-sensitive virus and receiving antiretroviral therapy. To investigate the importance of this potential route to drug resistance, we developed a bioinformatics pipeline to detect superinfection from routinely collected genotyping data, and assessed whether superinfection contributed to increased drug resistance in a large European cohort of viremic, drug treated patients.
Lingua originaleEnglish
pagine (da-a)537-537
Numero di pagine1
RivistaBMC Infectious Diseases
Volume13
DOI
Stato di pubblicazionePubblicato - 2013

Keywords

  • antiretroviral therapy
  • drug resistant
  • hiv
  • resistance

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