Successful treatment of multidrug-resistant Acinetobacter baumannii ventriculitis with intrathecal and intravenous colistin

Gennaro De Pascale, Angelo Pompucci, Teresa Spanu, Riccardo Maviglia, Giuseppe Bello, Annunziato Mangiola, Giancarlo Scoppettuolo

Risultato della ricerca: Contributo in rivistaArticolo in rivista

21 Citazioni (Scopus)

Abstract

Acinetobacter baumannii (AB) nosocomial infections, especially those due to multi-drug resistant (MDR) strains, are increasingly detected. We report a case of a 42-year-old male patient affected by low-grade ependymoma who developed AB-MDR post-neurosurgical ventriculitis. Initially, because of in vitro susceptibility, we used a combination of intravenous colistin and tigecycline. This treatment resulted in the improvement of the patient's initial condition. However, soon after, the infection relapsed; tigecycline was stopped and treatment with intrathecal colistin was initiated. Cure was achieved by continuing this treatment for approximately three weeks, without adverse effects.
Lingua originaleEnglish
pagine (da-a)957-960
Numero di pagine4
RivistaMINERVA ANESTESIOLOGICA
Volume76
Stato di pubblicazionePubblicato - 2010

Keywords

  • VENTRICULITIS
  • acinetobacter

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