Successful multimodal treatment of a breast cancer patient with a recurrence invading the chest wall

Stefano Margaritora, Giovanni Scambia, Maria Gabriella Ferrandina, Giacomo Corrado, Vanda Salutari, Alessio Piraino, Alessandro Lucidi, Anna Elvira Di Stefano

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

We describe successful operative management of a solitary breast cancer metastasis in the chest wall after complete response with concomitant non-pegylated liposomal doxorubicin (NPLD) and docetaxel followed by sternal rib resection with prosthetic reconstruction. We report a case of a 41-year-old woman who had a breast cancer recurrence infiltrating neighboring osteo-cartilage of the left sternal body, the cartilaginous portion of the third and fourth ipsilateral ribs and was inseparable from the rear side pectoral reaching deep into contiguity with the pericardium. After 6 cycles of chemotherapy with NPLD plus docetaxel, sternal rib resection with prosthetic reconstruction was performed. Histological examination did not show any evidence of residual tumor. At 9 months of follow-up, the patient appears free of disease. Our case demonstrates that a multimodal approach in patients with chest wall recurrence of breast cancer without distant metastasis, may be safe and effective for maintaining a good quality of life.
Lingua originaleEnglish
pagine (da-a)49-52
Numero di pagine4
RivistaJournal of Chemotherapy
Volume23
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols
  • Breast Neoplasms
  • Chemotherapy, Adjuvant
  • Doxorubicin
  • Female
  • Humans
  • Neoplasm Invasiveness
  • Neoplasm Metastasis
  • Neoplasm Recurrence, Local
  • Polyethylene Glycols
  • Reconstructive Surgical Procedures
  • Ribs
  • Taxoids
  • Thoracic Wall

Fingerprint

Entra nei temi di ricerca di 'Successful multimodal treatment of a breast cancer patient with a recurrence invading the chest wall'. Insieme formano una fingerprint unica.

Cita questo