Study of cellular toxicity in vitro of two resins for orthodontic use

Pier Carmine Passarelli*, S. SACCOMANNO, Paolo De Angelis, A. ROMEO, G. B. PICCIRILLO, V. DESANTIS, Cristina Grippaudo, Antonio D'Addona

*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivistaArticolopeer review

Abstract

Abstract. – OBJECTIVE: The objective of this work is to compare cellular toxicity in vitro of two resins for orthodontic use: an auto-polymerizable composite and a photo-polymerizable composite.\r\nMATERIALS AND METHODS: Samples were obtained by joining a couple of steel orthodontic brackets by using auto-polymerizing or photo-polymerizing resin. We used a halogen lamp, a mini LED lamp and a fast LED lamp used for orthodontics cure for 40 seconds. The 3T3 Swiss cellular line of fibroblasts was used. The samples obtained were used to determine the cellular toxicity in vitro using the Neutral Red Up-take (NRU) and the 3-(4,5-dimethylthiazol- 2-Yl)-2,5-diphenyltetrazolium bromide\r\n(MTT) assay.\r\nRESULTS: Toxicity of the extract appraised at a low level at MTT and NRU assays. There were statistically relevant differences between the toxicity induced by the auto-polymerizing material and the toxicity induced by the photo-polymerizing composite material, polymerized with the blue-light lamp (p < 0.001) and with the mini LED\r\nlamp (p < 0.05).\r\nCONCLUSIONS: From the data collected in this study, we can conclude that both resins show a low level of cytotoxicity that, in the case of photochemical polymerizing resin, depends on the characteristics of the lamp.
Lingua originaleInglese
pagine (da-a)930-934
Numero di pagine5
RivistaEuropean Review for Medical and Pharmacological Sciences
Volume24
Numero di pubblicazione2
DOI
Stato di pubblicazionePubblicato - 2020

All Science Journal Classification (ASJC) codes

  • Farmacologia (medica)

Keywords

  • citotoxicity
  • composites

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