Stereotyped B-cell receptor is an independent risk factor of chronic lymphocytic leukemia transformation to Richter syndrome

Luca Laurenti, Maurizio Martini, Luigi Maria Larocca, Davide Rossi, Valeria Spina, Michaela Cerri, Silvia Rasi, Clara Deambrogi, Lorenzo De Paoli, Rossana Maffei, Francesco Forconi, Francesco Bertoni, Emanuele Zucca, Claudio Agostinelli, Antonello Cabras, Marco Lucioni, Michele Magni, Silvia Deaglio, Marco Ladetto, Joseph F. NomdedeuCaroline Besson, Antonio Ramponi, Vincenzo Canzonieri, Marco Paulli, Roberto Marasca, Antonino Carbone, Stefano A. Pileri, Valter Gattei, Gianluca Gaidano

Risultato della ricerca: Contributo in rivistaArticolo in rivista

130 Citazioni (Scopus)

Abstract

Few biological prognosticators are useful for prediction of Richter syndrome (RS), representing the transformation of chronic lymphocytic leukemia (CLL) to aggressive lymphoma. Stereotyped B-cell receptors (BCR) may have prognostic effect in CLL progression. We tested the prognostic effect of stereotyped BCR for predicting RS transformation.
Lingua originaleEnglish
pagine (da-a)4415-4422
Numero di pagine8
RivistaClinical Cancer Research
Volume15
DOI
Stato di pubblicazionePubblicato - 2009

Keywords

  • Aged
  • Cohort Studies
  • Disease Progression
  • Female
  • Gene Frequency
  • Genetic Predisposition to Disease
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell
  • Lymphoma
  • Male
  • Middle Aged
  • Neoplasm Invasiveness
  • Polymorphism, Genetic
  • Proto-Oncogene Proteins c-bcr
  • Risk Factors
  • Syndrome

Fingerprint

Entra nei temi di ricerca di 'Stereotyped B-cell receptor is an independent risk factor of chronic lymphocytic leukemia transformation to Richter syndrome'. Insieme formano una fingerprint unica.

Cita questo