TY - JOUR
T1 - State and trait anxiety and depression in patients with primary brain tumors
before and after surgery: 1-year longitudinal study
AU - D'Angelo, Cristina
AU - Mirijello, Antonio
AU - Leggio, Lorenzo
AU - Ferrulli, Anna
AU - Carotenuto, Vincenzo
AU - Icolaro, Nadia
AU - Miceli, Antonio
AU - D'Angelo, Vincenzo
AU - Gasbarrini, Giovanni Battista
AU - Addolorato, Giovanni
PY - 2008
Y1 - 2008
N2 - OBJECT: The aim in this study was to assess the state and trait types of anxiety as well as current depression before and after surgery in patients affected by brain tumors. The relationships between these affective disorders and the patient's sex, tumor histology, and laterality of the tumor were also evaluated.
METHODS: A total of 72 patients affected by a primary brain tumor were enrolled in the study. Histological grades were assigned according to the World Health Organization classification. State and trait anxiety were assessed using the
State and Trait Anxiety Inventory; current depression was assessed using the Zung Self-Rating Depression Scale. Cognitive impairment was assessed using the 10-item Short Portable Mental Status Questionnaire. Psychometric evaluation was assessed before surgery and at 1, 3, 6, and 12 months after surgery.
RESULTS: Before brain surgery, 62.5% of patients showed state anxiety, 50% of
patients showed trait anxiety, and 9.7% of patients showed current depression.
During the follow-up period there was no significant variation in the percentage of patients with state anxiety (p=0.416) and trait anxiety (p=0.7), whereas a significant increase in the percentage of those with current depression was found(p<0.0001), in particular at 1 month (p=0.002) and 3 months (p=0.039) after surgical treatment. The tumor's laterality and histology showed no correlation
with psychometric variables, whereas a relationship between the presence of trait anxiety at the enrollment and current depression after surgery (p<0.0001) was found.
CONCLUSIONS: Patients affected by brain tumors frequently experience affective
disorders. After brain surgery, a depressive state can develop. The psychometric assessment could be useful in these patients for quick recognition of psychological disorders.
AB - OBJECT: The aim in this study was to assess the state and trait types of anxiety as well as current depression before and after surgery in patients affected by brain tumors. The relationships between these affective disorders and the patient's sex, tumor histology, and laterality of the tumor were also evaluated.
METHODS: A total of 72 patients affected by a primary brain tumor were enrolled in the study. Histological grades were assigned according to the World Health Organization classification. State and trait anxiety were assessed using the
State and Trait Anxiety Inventory; current depression was assessed using the Zung Self-Rating Depression Scale. Cognitive impairment was assessed using the 10-item Short Portable Mental Status Questionnaire. Psychometric evaluation was assessed before surgery and at 1, 3, 6, and 12 months after surgery.
RESULTS: Before brain surgery, 62.5% of patients showed state anxiety, 50% of
patients showed trait anxiety, and 9.7% of patients showed current depression.
During the follow-up period there was no significant variation in the percentage of patients with state anxiety (p=0.416) and trait anxiety (p=0.7), whereas a significant increase in the percentage of those with current depression was found(p<0.0001), in particular at 1 month (p=0.002) and 3 months (p=0.039) after surgical treatment. The tumor's laterality and histology showed no correlation
with psychometric variables, whereas a relationship between the presence of trait anxiety at the enrollment and current depression after surgery (p<0.0001) was found.
CONCLUSIONS: Patients affected by brain tumors frequently experience affective
disorders. After brain surgery, a depressive state can develop. The psychometric assessment could be useful in these patients for quick recognition of psychological disorders.
KW - anxiety
KW - depression
KW - primary brain tumors
KW - anxiety
KW - depression
KW - primary brain tumors
UR - http://hdl.handle.net/10807/33363
M3 - Article
SN - 0022-3085
VL - 108
SP - 281
EP - 286
JO - Journal of Neurosurgery
JF - Journal of Neurosurgery
ER -