Solitary Peutz-Jeghers Polyp in a Paediatric Patient

Lorenzo Nanni, Giuseppe Retrosi, Fabio Maria Vecchio, Carlo Manzoni, Raffaella Canali, Claudio Pintus, Gaia Busato

Risultato della ricerca: Contributo in rivistaArticolo in rivista

13 Citazioni (Scopus)

Abstract

Hamartomatous polyps of Peutz-Jeghers are mostly found in patients affected by Peutz-Jeghers syndrome (PJS), but they can be rarely encountered in the general population. It is unclear whether a solitary Peutz-Jeghers polyp (PJP) is an incomplete form of PJS or a separate entity. We report a case of solitary PJP in a paediatric patient in whom the other features of PJS were absent. The patient underwent laparotomy due to small bowel intussusception secondary to an ileac polyp. Histological examination showed the characteristic features of PJP, but the patient did not fulfill the WHO criteria for PJS diagnosis (negative family history for PJS and absence of mucocutaneous pigmentation); moreover analysis of the STK11/LKB1 gene did not reveal any genomic abnormality. The clinical and investigative findings in our case suggest that the solitary PJP can be considered a different clinical entity from PJS.
Lingua originaleEnglish
pagine (da-a)452-456
Numero di pagine5
RivistaCase Reports in Gastroenterology
Volume4
DOI
Stato di pubblicazionePubblicato - 2010

Keywords

  • peutz jeghers

Fingerprint Entra nei temi di ricerca di 'Solitary Peutz-Jeghers Polyp in a Paediatric Patient'. Insieme formano una fingerprint unica.

Cita questo