Smoking habit and secretor status modify perception of methacholine-induced bronchoconstriction

Flaminio Mormile, A. Del Bono, M. De Rosa, G. Culla, M. Collaro, A. Di Napoli, G. Croce, G. Ciappi

Risultato della ricerca: Contributo in rivistaAbstract

Abstract

The perceived dyspnea measured on a 10-cm visual analog scale per one percent decrease of FEV1 during bronchial challenge with methacholine was measured in a large group of travertine workers. The perceived dyspnea for FEV1 reductions up to 10-15% was lower in smokers , suggesting either a selection of less symptomatic workers among smokers and/or a smoke-related damage of sensitive nerves. Genetic factors seem also involved, as the ABO secretor status was a significant modifying variable of perceived dyspnea
Lingua originaleEnglish
pagine (da-a)a 623-a 623
Numero di pagine1
RivistaAmerican Journal of Respiratory and Critical Care Medicine
Volume153
Stato di pubblicazionePubblicato - 1996

Keywords

  • ABO secretor status
  • dyspnea perception
  • methacholine
  • smoking

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