small bowel neoplasms in patients undergoing video capsule endoscopy: a multicenter european study

Emanuele Rondonotti, Marco Pennazio, Ervin Toth, Pedro Menchen, Maria Elena Riccioni, Giovanni De Palma, Francesco Scotto, Danny De Looze, Thomas Pachofsky, Ilja Tacheci, Troels Havelund, Gilberto Couto, Anca Trifan, Alex Kofokotsios, Renato Cannizzaro, Enrique Perez Cuadrado, Roberto De Franchis

Risultato della ricerca: Contributo in rivistaEditoriale in rivista / quotidiano

173 Citazioni (Scopus)


Background: small bowel (SB) tumors account for 1-3% of all GI neoplasms. Recent studies with video capsule endoscopy (VCE) suggest that the frequency of these tumors may be substantially higher than previusly reported.Aim of the study: to evaluate frequency, clinical presentation, diagnostic/therapeutic work-up and endoscopic appearance of SB tumors in a large population of patients undergoing VCE.Methods: identification by specific questionnaire of all patients with VCE findings suggesting SB tumors and histological confirmation of the neoplasm seen in 29 centers of 10 European counries Results:124/5129 patients undergoing VCE (2.4%) had SB tumors (112 primitive,12 metastatic).Indication for VCE: obscure GI bleeding (108 patients), abdominal pain (9), research for primitive neoplasm (6), diarrhea with malabsorption (1). 80.6% of the tumors were identified solely based on VCE findings. 55 patients underwent VCE as the thierd procedure after a negative bidiretional endoscopy; 69 underwent a mean of 1.47 examinations before VCE. the lesions were single in 89.5% of cases, multiple in 10.5%. VCE retention occurred in 9.8% of patients. After VCE, 54 patients underwent 57 other examinations before treatment. The diagnostic yield of enteroscopy performed before VCE was 9%, compared with 77% when performed after a positive VCE examination (p<0.0001). Treatment was surgery in 92% of cases. Conclusions: In our series the frequency of SB tumors was 2.4%.The majority of patients had obscure GI bleeding.VCE results led directly to treatment in 47% of patients, and oriented the subsequent endoscopic work up in 28%.
Lingua originaleEnglish
pagine (da-a)488-495
Numero di pagine8
Stato di pubblicazionePubblicato - 2008


  • capsule endoscopy
  • small bowel neoplasms


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