Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients

Massimiliano Fabbiani; Mauro Zaccarelli; Pierfrancesco Grima; Mattia Prosperi; Iuri Fanti; Manuela Colafigli; Alessandro D'Avino; Annalisa Mondi; Alberto Borghetti; Massimo Fantoni; Roberto Cauda; Simona Di Giambenedetto

doi:10.1186/1471-2334-14-26

Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients

Massimiliano Fabbiani, Mauro Zaccarelli, Pierfrancesco Grima, Mattia Prosperi, Iuri Fanti, Manuela Colafigli, Alessandro D'Avino, Annalisa Mondi, Alberto Borghetti, Massimo Fantoni, Roberto Cauda, Simona Di Giambenedetto

Risultato della ricerca: Contributo in rivista › Articolo in rivista › peer review

13 Citazioni (Scopus)

Abstract

Efavirenz (EFV) administration is still controversial for its high rates of interruption mainly related to central nervous system side effects (CNS-SE). Aim of the study was to define if single tablet regimen (STR) as compared to bis-in-die (BID) or once-daily (OD) with ≥2 pills-a-day EFV formulations reduced the risk of interruption.

Lingua originale	English
pagine (da-a)	26-26
Numero di pagine	1
Rivista	BMC Public Health
Volume	14
DOI	https://doi.org/10.1186/1471-2334-14-26
Stato di pubblicazione	Pubblicato - 2014

Keywords

Efavirenz
antiretroviral
nervous system
therapy

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Fabbiani, M., Zaccarelli, M., Grima, P., Prosperi, M., Fanti, I., Colafigli, M., D'Avino, A., Mondi, A., Borghetti, A., Fantoni, M., Cauda, R., & Di Giambenedetto, S. (2014). Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients. BMC Public Health, 14, 26-26. https://doi.org/10.1186/1471-2334-14-26

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abstract = "Efavirenz (EFV) administration is still controversial for its high rates of interruption mainly related to central nervous system side effects (CNS-SE). Aim of the study was to define if single tablet regimen (STR) as compared to bis-in-die (BID) or once-daily (OD) with ≥2 pills-a-day EFV formulations reduced the risk of interruption.",

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author = "Massimiliano Fabbiani and Mauro Zaccarelli and Pierfrancesco Grima and Mattia Prosperi and Iuri Fanti and Manuela Colafigli and Alessandro D'Avino and Annalisa Mondi and Alberto Borghetti and Massimo Fantoni and Roberto Cauda and {Di Giambenedetto}, Simona",

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Fabbiani, M, Zaccarelli, M, Grima, P, Prosperi, M, Fanti, I, Colafigli, M, D'Avino, A, Mondi, A, Borghetti, A, Fantoni, M, Cauda, R & Di Giambenedetto, S 2014, 'Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients', BMC Public Health, vol. 14, pagg. 26-26. https://doi.org/10.1186/1471-2334-14-26

TY - JOUR

T1 - Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients

AU - Fabbiani, Massimiliano

AU - Zaccarelli, Mauro

AU - Grima, Pierfrancesco

AU - Prosperi, Mattia

AU - Fanti, Iuri

AU - Colafigli, Manuela

AU - D'Avino, Alessandro

AU - Mondi, Annalisa

AU - Borghetti, Alberto

AU - Fantoni, Massimo

AU - Cauda, Roberto

AU - Di Giambenedetto, Simona

PY - 2014

Y1 - 2014

N2 - Efavirenz (EFV) administration is still controversial for its high rates of interruption mainly related to central nervous system side effects (CNS-SE). Aim of the study was to define if single tablet regimen (STR) as compared to bis-in-die (BID) or once-daily (OD) with ≥2 pills-a-day EFV formulations reduced the risk of interruption.

AB - Efavirenz (EFV) administration is still controversial for its high rates of interruption mainly related to central nervous system side effects (CNS-SE). Aim of the study was to define if single tablet regimen (STR) as compared to bis-in-die (BID) or once-daily (OD) with ≥2 pills-a-day EFV formulations reduced the risk of interruption.

KW - Efavirenz

KW - antiretroviral

KW - nervous system

KW - therapy

KW - Efavirenz

KW - antiretroviral

KW - nervous system

KW - therapy

UR - http://hdl.handle.net/10807/50891

U2 - 10.1186/1471-2334-14-26

DO - 10.1186/1471-2334-14-26

M3 - Article

SN - 1471-2458

VL - 14

SP - 26

EP - 26

JO - BMC Public Health

JF - BMC Public Health

ER -

Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients

Abstract

Keywords

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