Single-step multimodal locoregional treatment for unresectable hepatocellular carcinoma: balloon-occluded percutaneous radiofrequency thermal ablation (BO-RFA) plus transcatheter arterial chemoembolization (TACE)

Roberto Iezzi; Valentina Cesario; Luisa Siciliani; Mariachiara Campanale; Anna Maria De Gaetano; Massimo Siciliano; Salvatore Agnes; Felice Giuliante; Antonio Grieco; Maurizio Pompili; Gian Ludovico Rapaccini; Antonio Gasbarrini; Lorenzo Bonomo

doi:10.1007/s11547-012-0914-7

Single-step multimodal locoregional treatment for unresectable hepatocellular carcinoma: balloon-occluded percutaneous radiofrequency thermal ablation (BO-RFA) plus transcatheter arterial chemoembolization (TACE)

Roberto Iezzi, Valentina Cesario, Luisa Siciliani, Mariachiara Campanale, Anna Maria De Gaetano, Massimo Siciliano, Salvatore Agnes, Felice Giuliante, Antonio Grieco, Maurizio Pompili, Gian Ludovico Rapaccini, Antonio Gasbarrini, Lorenzo Bonomo

Risultato della ricerca: Contributo in rivista › Articolo in rivista

12 Citazioni (Scopus)

Abstract

This study was undertaken to evaluate the feasibility, safety and efficacy of a new combined single-step therapy in patients with unresectable multinodular unilobar hepatocellular carcinoma (HCC), with at least one lesion >3 cm, with balloon-occluded radiofrequency ablation (BO-RFA) plus transcatheter arterial chemoembolization (TACE) of the main lesion and TACE of the other lesions. The second purpose of our study was to compare the initial effects in terms of tumour necrosis of this new combined therapy with those obtained in a matched population treated with TACE alone in a singlestep treatment in our centre in the previous year.

Lingua originale	English
pagine (da-a)	555-569
Numero di pagine	15
Rivista	LA RADIOLOGIA MEDICA
Volume	118
DOI	https://doi.org/10.1007/s11547-012-0914-7
Stato di pubblicazione	Pubblicato - 2013

Keywords

Aged
Algorithms
Antibiotic Prophylaxis
Antineoplastic Combined Chemotherapy Protocols
Balloon Occlusion
Carboplatin
Carcinoma, Hepatocellular
Catheter Ablation
Chemoembolization, Therapeutic
Combined Modality Therapy
Ethiodized Oil
Female
Gelatin Sponge, Absorbable
Humans
Liver Neoplasms
Male
Middle Aged
Patient Safety
Pilot Projects
Treatment Outcome

Accesso al documento

10.1007/s11547-012-0914-7

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Iezzi, R., Cesario, V., Siciliani, L., Campanale, M., De Gaetano, A. M., Siciliano, M., Agnes, S., Giuliante, F., Grieco, A., Pompili, M., Rapaccini, G. L., Gasbarrini, A., & Bonomo, L. (2013). Single-step multimodal locoregional treatment for unresectable hepatocellular carcinoma: balloon-occluded percutaneous radiofrequency thermal ablation (BO-RFA) plus transcatheter arterial chemoembolization (TACE). LA RADIOLOGIA MEDICA, 118, 555-569. https://doi.org/10.1007/s11547-012-0914-7

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title = "Single-step multimodal locoregional treatment for unresectable hepatocellular carcinoma: balloon-occluded percutaneous radiofrequency thermal ablation (BO-RFA) plus transcatheter arterial chemoembolization (TACE)",

abstract = "This study was undertaken to evaluate the feasibility, safety and efficacy of a new combined single-step therapy in patients with unresectable multinodular unilobar hepatocellular carcinoma (HCC), with at least one lesion >3 cm, with balloon-occluded radiofrequency ablation (BO-RFA) plus transcatheter arterial chemoembolization (TACE) of the main lesion and TACE of the other lesions. The second purpose of our study was to compare the initial effects in terms of tumour necrosis of this new combined therapy with those obtained in a matched population treated with TACE alone in a singlestep treatment in our centre in the previous year.",

keywords = "Aged, Algorithms, Antibiotic Prophylaxis, Antineoplastic Combined Chemotherapy Protocols, Balloon Occlusion, Carboplatin, Carcinoma, Hepatocellular, Catheter Ablation, Chemoembolization, Therapeutic, Combined Modality Therapy, Ethiodized Oil, Female, Gelatin Sponge, Absorbable, Humans, Liver Neoplasms, Male, Middle Aged, Patient Safety, Pilot Projects, Treatment Outcome, Aged, Algorithms, Antibiotic Prophylaxis, Antineoplastic Combined Chemotherapy Protocols, Balloon Occlusion, Carboplatin, Carcinoma, Hepatocellular, Catheter Ablation, Chemoembolization, Therapeutic, Combined Modality Therapy, Ethiodized Oil, Female, Gelatin Sponge, Absorbable, Humans, Liver Neoplasms, Male, Middle Aged, Patient Safety, Pilot Projects, Treatment Outcome",

author = "Roberto Iezzi and Valentina Cesario and Luisa Siciliani and Mariachiara Campanale and {De Gaetano}, {Anna Maria} and Massimo Siciliano and Salvatore Agnes and Felice Giuliante and Antonio Grieco and Maurizio Pompili and Rapaccini, {Gian Ludovico} and Antonio Gasbarrini and Lorenzo Bonomo",

year = "2013",

doi = "10.1007/s11547-012-0914-7",

language = "English",

volume = "118",

pages = "555--569",

journal = "LA RADIOLOGIA MEDICA",

issn = "0033-8362",

publisher = "- Milano : Springer Verlag Italia -Turin Italy: Edizioni Minerva Medica",

}

Iezzi, R, Cesario, V, Siciliani, L, Campanale, M, De Gaetano, AM, Siciliano, M, Agnes, S , Giuliante, F, Grieco, A, Pompili, M, Rapaccini, GL, Gasbarrini, A & Bonomo, L 2013, 'Single-step multimodal locoregional treatment for unresectable hepatocellular carcinoma: balloon-occluded percutaneous radiofrequency thermal ablation (BO-RFA) plus transcatheter arterial chemoembolization (TACE)', LA RADIOLOGIA MEDICA, vol. 118, pagg. 555-569. https://doi.org/10.1007/s11547-012-0914-7

Single-step multimodal locoregional treatment for unresectable hepatocellular carcinoma: balloon-occluded percutaneous radiofrequency thermal ablation (BO-RFA) plus transcatheter arterial chemoembolization (TACE). / Iezzi, Roberto; Cesario, Valentina; Siciliani, Luisa et al.
In: LA RADIOLOGIA MEDICA, Vol. 118, 2013, pag. 555-569.

Risultato della ricerca: Contributo in rivista › Articolo in rivista

TY - JOUR

T1 - Single-step multimodal locoregional treatment for unresectable hepatocellular carcinoma: balloon-occluded percutaneous radiofrequency thermal ablation (BO-RFA) plus transcatheter arterial chemoembolization (TACE)

AU - Iezzi, Roberto

AU - Cesario, Valentina

AU - Siciliani, Luisa

AU - Campanale, Mariachiara

AU - De Gaetano, Anna Maria

AU - Siciliano, Massimo

AU - Agnes, Salvatore

AU - Giuliante, Felice

AU - Grieco, Antonio

AU - Pompili, Maurizio

AU - Rapaccini, Gian Ludovico

AU - Gasbarrini, Antonio

AU - Bonomo, Lorenzo

PY - 2013

Y1 - 2013

N2 - This study was undertaken to evaluate the feasibility, safety and efficacy of a new combined single-step therapy in patients with unresectable multinodular unilobar hepatocellular carcinoma (HCC), with at least one lesion >3 cm, with balloon-occluded radiofrequency ablation (BO-RFA) plus transcatheter arterial chemoembolization (TACE) of the main lesion and TACE of the other lesions. The second purpose of our study was to compare the initial effects in terms of tumour necrosis of this new combined therapy with those obtained in a matched population treated with TACE alone in a singlestep treatment in our centre in the previous year.

AB - This study was undertaken to evaluate the feasibility, safety and efficacy of a new combined single-step therapy in patients with unresectable multinodular unilobar hepatocellular carcinoma (HCC), with at least one lesion >3 cm, with balloon-occluded radiofrequency ablation (BO-RFA) plus transcatheter arterial chemoembolization (TACE) of the main lesion and TACE of the other lesions. The second purpose of our study was to compare the initial effects in terms of tumour necrosis of this new combined therapy with those obtained in a matched population treated with TACE alone in a singlestep treatment in our centre in the previous year.

KW - Aged

KW - Algorithms

KW - Antibiotic Prophylaxis

KW - Antineoplastic Combined Chemotherapy Protocols

KW - Balloon Occlusion

KW - Carboplatin

KW - Carcinoma, Hepatocellular

KW - Catheter Ablation

KW - Chemoembolization, Therapeutic

KW - Combined Modality Therapy

KW - Ethiodized Oil

KW - Female

KW - Gelatin Sponge, Absorbable

KW - Humans

KW - Liver Neoplasms

KW - Male

KW - Middle Aged

KW - Patient Safety

KW - Pilot Projects

KW - Treatment Outcome

KW - Aged

KW - Algorithms

KW - Antibiotic Prophylaxis

KW - Antineoplastic Combined Chemotherapy Protocols

KW - Balloon Occlusion

KW - Carboplatin

KW - Carcinoma, Hepatocellular

KW - Catheter Ablation

KW - Chemoembolization, Therapeutic

KW - Combined Modality Therapy

KW - Ethiodized Oil

KW - Female

KW - Gelatin Sponge, Absorbable

KW - Humans

KW - Liver Neoplasms

KW - Male

KW - Middle Aged

KW - Patient Safety

KW - Pilot Projects

KW - Treatment Outcome

UR - http://hdl.handle.net/10807/60744

U2 - 10.1007/s11547-012-0914-7

DO - 10.1007/s11547-012-0914-7

M3 - Article

SN - 0033-8362

VL - 118

SP - 555

EP - 569

JO - LA RADIOLOGIA MEDICA

JF - LA RADIOLOGIA MEDICA

ER -