Severe cushing’s syndrome related to a small pulmonary carcinoid with widespread dissemination

Filippo Lococo, Aurelio Negro, Francesca Zanelli, Riccardo Valli, Angelina Filice, Cristian Rapicetta, Massimiliano Paci

Risultato della ricerca: Contributo in rivistaArticolo in rivista

2 Citazioni (Scopus)

Abstract

Cushing’s syndrome (CS) is characterized by the overproduction of cortisol that may result in significant morbidity and mortality if left untreated. CS is very rarely caused by ectopic adrenocorticotropic hormone production from several tumors, although pulmonary neuroendocrine tumors (pNETs) are the most common etiology. It is controversial whether such tumors are more clinically aggressive than other pNETs. We herein report an unusual case of severe ectopic CS caused by a small pulmonary carcinoid in the lung with massive neoplastic dissemination to the liver. We highlight and discuss the unusual clinical onset, with diagnostic and therapeutic criticism, of this rare entity.
Lingua originaleEnglish
pagine (da-a)477-480
Numero di pagine4
RivistaINTERNAL MEDICINE
Volume54
DOI
Stato di pubblicazionePubblicato - 2015

Keywords

  • Bronchial carcinoids
  • Cushing’s syndrome
  • PET/CT scan

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