Severe acute hypertriglyeridemia during acute lymphoblastic leukemia induction successfully treated with plasmapheresis

Palma Maurizi, Vita Ridola, Paola Sabrina Buonuomo, Rossana Putzulu, Domenico Pietrini, Riccardo Riccardi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

29 Citazioni (Scopus)

Abstract

Children suffering from Acute Lymphoblastic Leukaemia (ALL) treated with asparaginase and corticosteroids are at risk of developing severe lipid abnormalities. The authors report the case of a 10-year-old male with extremely high plasma triglyceride concentrations (4,000 mg/dl) during the induction phase of ALL associated with mild pancreatitis. Hypertriglyceridemia was successfully managed with plasmapheresis with a decrease in triglyceride levels to 590 mg/dl. Apheresis appears to be safe and effective in reducing hypertriglyceridemia and preventing related complications
Lingua originaleEnglish
pagine (da-a)378-380
Numero di pagine3
RivistaPEDIATRIC BLOOD & CANCER
Volume50
Stato di pubblicazionePubblicato - 2006

Keywords

  • acute lymphoblastic leukemia
  • hypertriglyceridemia
  • plasmapheresis

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