Sensitivity of breast MRI for ductal carcinoma in situ appearing as microcalcifications only on mammography

Paolo Belli, Pierluigi Rinaldi, Chiara Buccheri, Michela Giuliani, Enida Bufi, Maurizio Romani, Federica Patrolecco, Lorenzo Bonomo

Risultato della ricerca: Contributo in rivistaArticolo in rivista

2 Citazioni (Scopus)

Abstract

Purpose This study aims to investigate sensitivity of breast magnetic resonance imaging (MRI) for mammographic microcalcifications-only ductal carcinoma in situ (DCIS), based on its histopathology and mammographic extent of microcalcifications. Methods Mammograms were reviewed to measure the extent of microcalcifications. Sensitivity of MRI was calculated in the overall study population and in groups differing for DCIS nuclear grade, microinvasivity, and microcalcifications' extent. Results Overall sensitivity of MRI was 78.3% for dynamic contrast enhanced and 66.7% for diffusion-weighted imaging and did not vary with nuclear grade and microinvasivity, while it increased with larger extent of microcalcifications (ExpB=1.063–1.046, P=.037–.013). Conclusions Mammographic extent of microcalcifications positively affects sensitivity of breast MRI.
Lingua originaleEnglish
pagine (da-a)1207-1212
Numero di pagine6
RivistaClinical Imaging
Volume40
DOI
Stato di pubblicazionePubblicato - 2016

Keywords

  • Breast Neoplasms
  • Calcinosis
  • Carcinoma, Intraductal, Noninfiltrating
  • DCE MRI
  • DWI MRI
  • Ductal carcinoma in situ (DCIS)
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Mammography
  • Microcalcifications
  • Middle Aged
  • Radiology, Nuclear Medicine and Imaging
  • Sensitivity and Specificity

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