Semaphorin pathways orchestrate osteogenesis

Luca Tamagnone, Silvia Giordano

Risultato della ricerca: Contributo in rivistaArticolo in rivista

15 Citazioni (Scopus)


Semaphorins regulate a variety of biological processes, including axon guidance, neuronal migration, angiogenesis, cardiogenesis and immune responses. Semaphorin 6D is now shown to regulate osteoclast function during bone development, through its association with its receptor plexinA1. This activity implicates a signalling pathway known to transcriptionally regulate cell differentiation and involves the receptor Trem2 and the adaptor DAP12. © 2006 Nature Publishing Group.
Lingua originaleEnglish
pagine (da-a)545-547
Numero di pagine3
RivistaNature Cell Biology
Stato di pubblicazionePubblicato - 2006


  • Cell Biology


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