Safety and efficacy of abobotulinumtoxinA for hemiparesis in adults with upper limb spasticity after stroke or traumatic brain injury: a double-blind randomised controlled trial

Anna Rita Bentivoglio

doi:10.1016/S1474-4422(15)00216-1

Safety and efficacy of abobotulinumtoxinA for hemiparesis in adults with upper limb spasticity after stroke or traumatic brain injury: a double-blind randomised controlled trial

Anna Rita Bentivoglio

Risultato della ricerca: Contributo in rivista › Articolo

101 Citazioni (Scopus)

Abstract

Resistance from antagonistic muscle groups might be a crucial factor reducing function in chronic hemiparesis. The resistance due to spastic co-contraction might be reduced by botulinum toxin injections. We assessed the effects of abobotulinumtoxinA injection in the upper limb muscles on muscle tone, spasticity, active movement, and function.

Lingua originale	Inglese
pagine (da-a)	992-1001
Numero di pagine	10
Rivista	The Lancet
Volume	14
DOI	https://doi.org/10.1016/S1474-4422(15)00216-1
Stato di pubblicazione	Pubblicato - 2015

Keywords

Acetylcholine Release Inhibitors
Adult
Botulinum Toxins, Type A
Brain Injuries
Double-Blind Method
Female
Humans
Injections, Intramuscular
Male
Middle Aged
Muscle Spasticity
Paresis
Stroke
Treatment Outcome
Upper Extremity

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10.1016/S1474-4422(15)00216-1

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title = "Safety and efficacy of abobotulinumtoxinA for hemiparesis in adults with upper limb spasticity after stroke or traumatic brain injury: a double-blind randomised controlled trial",

abstract = "Resistance from antagonistic muscle groups might be a crucial factor reducing function in chronic hemiparesis. The resistance due to spastic co-contraction might be reduced by botulinum toxin injections. We assessed the effects of abobotulinumtoxinA injection in the upper limb muscles on muscle tone, spasticity, active movement, and function.",

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AU - Bentivoglio, Anna Rita

PY - 2015

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N2 - Resistance from antagonistic muscle groups might be a crucial factor reducing function in chronic hemiparesis. The resistance due to spastic co-contraction might be reduced by botulinum toxin injections. We assessed the effects of abobotulinumtoxinA injection in the upper limb muscles on muscle tone, spasticity, active movement, and function.

AB - Resistance from antagonistic muscle groups might be a crucial factor reducing function in chronic hemiparesis. The resistance due to spastic co-contraction might be reduced by botulinum toxin injections. We assessed the effects of abobotulinumtoxinA injection in the upper limb muscles on muscle tone, spasticity, active movement, and function.

KW - Acetylcholine Release Inhibitors

KW - Adult

KW - Botulinum Toxins, Type A

KW - Brain Injuries

KW - Double-Blind Method

KW - Female

KW - Humans

KW - Injections, Intramuscular

KW - Male

KW - Middle Aged

KW - Muscle Spasticity

KW - Paresis

KW - Stroke

KW - Treatment Outcome

KW - Upper Extremity

KW - Acetylcholine Release Inhibitors

KW - Adult

KW - Botulinum Toxins, Type A

KW - Brain Injuries

KW - Double-Blind Method

KW - Female

KW - Humans

KW - Injections, Intramuscular

KW - Male

KW - Middle Aged

KW - Muscle Spasticity

KW - Paresis

KW - Stroke

KW - Treatment Outcome

KW - Upper Extremity

UR - http://hdl.handle.net/10807/69797

U2 - 10.1016/S1474-4422(15)00216-1

DO - 10.1016/S1474-4422(15)00216-1

M3 - Article

SN - 0140-6736

VL - 14

SP - 992

EP - 1001

JO - The Lancet

JF - The Lancet

ER -

Safety and efficacy of abobotulinumtoxinA for hemiparesis in adults with upper limb spasticity after stroke or traumatic brain injury: a double-blind randomised controlled trial

Abstract

Keywords

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