Safety and efficacy of abobotulinumtoxinA for hemiparesis in adults with upper limb spasticity after stroke or traumatic brain injury: a double-blind randomised controlled trial

Anna Rita Bentivoglio, Jean-Michel Gracies, Allison Brashear, Robert Jech, Peter Mcallister, Marta Banach, Peter Valkovic, Heather Walker, Christina Marciniak, Thierry Deltombe, Alexander Skoromets, Svetlana Khatkova, Steven Edgley, Fatma Gul, France Catus, Beatrice Bois De Fer, Claire Vilain, Philippe Picaut, Z. Ayyoub, D. BensmailA. R Bentivoglio, F. Boyer, A. Csanyi, Z. Denes, P. Hedera, S. Isaacson, M. E. Isner-Horobeti, A. Kaminska, S. Kocer, T. Lejeune, P. Marque, M. O'Dell, O. Remy-Neris, B. Rubin, M. Rudzinska, D. Simpson, S. L. Timerbaeva, M. Vecchio, M. Wimmer

Risultato della ricerca: Contributo in rivistaArticolo in rivista

101 Citazioni (Scopus)

Abstract

Resistance from antagonistic muscle groups might be a crucial factor reducing function in chronic hemiparesis. The resistance due to spastic co-contraction might be reduced by botulinum toxin injections. We assessed the effects of abobotulinumtoxinA injection in the upper limb muscles on muscle tone, spasticity, active movement, and function.
Lingua originaleEnglish
pagine (da-a)992-1001
Numero di pagine10
RivistaThe Lancet
Volume14
DOI
Stato di pubblicazionePubblicato - 2015

Keywords

  • Acetylcholine Release Inhibitors
  • Adult
  • Botulinum Toxins, Type A
  • Brain Injuries
  • Double-Blind Method
  • Female
  • Humans
  • Injections, Intramuscular
  • Male
  • Middle Aged
  • Muscle Spasticity
  • Paresis
  • Stroke
  • Treatment Outcome
  • Upper Extremity

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