Safety and efficacy of abobotulinumtoxinA for hemiparesis in adults with upper limb spasticity after stroke or traumatic brain injury: a double-blind randomised controlled trial

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Abstract

Resistance from antagonistic muscle groups might be a crucial factor reducing function in chronic hemiparesis. The resistance due to spastic co-contraction might be reduced by botulinum toxin injections. We assessed the effects of abobotulinumtoxinA injection in the upper limb muscles on muscle tone, spasticity, active movement, and function.
Lingua originaleEnglish
pagine (da-a)992-1001
Numero di pagine10
RivistaThe Lancet
Volume14
DOI
Stato di pubblicazionePubblicato - 2015

Keywords

  • Acetylcholine Release Inhibitors
  • Adult
  • Botulinum Toxins, Type A
  • Brain Injuries
  • Double-Blind Method
  • Female
  • Humans
  • Injections, Intramuscular
  • Male
  • Middle Aged
  • Muscle Spasticity
  • Paresis
  • Stroke
  • Treatment Outcome
  • Upper Extremity

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