Role of minimally invasive surgery versus open approach in patients with early-stage uterine carcinosarcomas: a retrospective multicentric study

Giacomo Corrado*, Francesca Ciccarone, Francesco Cosentino, Francesco Legge, Andrea Rosati, Martina Arcieri, Luigi Carlo Turco, Camilla Certelli, Alex Federico, Enrico Vizza, Francesco Fanfani, Giovanni Scambia, Maria Gabriella Ferrandina

*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivistaArticolo

Abstract

Objective: The aim of this retrospective study was to compare surgical and survival outcome in only patients with early-stage UCSs managed by laparotomic surgery (LPT) versus minimally invasive surgery (MIS).\r\n\r\nMethods: Data were retrospectively collected in four Italian different institutions. Inclusion criteria were UCS diagnosis confirmed by the definitive histological examination, and stage I or II according to the FIGO staging system.\r\n\r\nResults: Between August 2000 and March 2019, the data relative to 170 patients bearing UCSs were collected: of these, 95 were defined as early-stage disease (stage I-II) based on the histological report at the primary surgery, and thus were included in this study. Forty-four patients were managed by LPT, and 51 patients were managed by MIS. The operative time was lower in the MIS group versus the LPT group (p value 0.021); the median estimated blood loss was less in the MIS group compared to the median of LPT group (p value < 0.0001). The length of hospital stay days was shorter in the MIS patients (p value < 0.0001). Overall, there were eight (8.4%) post-operative complications; of these, seven were recorded in the LPT group versus one in the MIS group (p value 0.023). There was no difference in the disease-free survival (DFS) and overall survival (OS) between the two groups.\r\n\r\nConclusion: There was no difference of oncologic outcome between the two approaches, in face of a more favourable peri-operative and post-operative profile in the MIS group.
Lingua originaleInglese
pagine (da-a)N/A-N/A
RivistaJournal of Cancer Research and Clinical Oncology
Numero di pubblicazioneN/A
DOI
Stato di pubblicazionePubblicato - 2020

All Science Journal Classification (ASJC) codes

  • Oncologia
  • Ricerca sul Cancro

Keywords

  • Minimally invasive surgery
  • Open surgery
  • Uterine carcinosarcoma

Fingerprint

Entra nei temi di ricerca di 'Role of minimally invasive surgery versus open approach in patients with early-stage uterine carcinosarcomas: a retrospective multicentric study'. Insieme formano una fingerprint unica.

Cita questo