Role of Clinical Pharmacology in the Development of Antiplatelet Drugs

Carlo Patrono

doi:10.1016/j.clinthera.2014.10.012

Role of Clinical Pharmacology in the Development of Antiplatelet Drugs

Carlo Patrono

Risultato della ricerca: Contributo in rivista › Articolo in rivista

5 Citazioni (Scopus)

Abstract

This review discusses the role of clinical pharmacology in the development of low-dose aspirin and other antiplatelet agents during the past 30 years, emphasizing the main determinants of several success stories as well as of complete failures in the field.

Lingua originale	English
pagine (da-a)	2096-2111
Numero di pagine	16
Rivista	Clinical Therapeutics
Volume	36
DOI	https://doi.org/10.1016/j.clinthera.2014.10.012
Stato di pubblicazione	Pubblicato - 2014
Pubblicato esternamente	Sì

Keywords

GPIIb/IIIa blockers
P2Y(12) blockers
PAR-1 antagonists
TP antagonists
aspirin

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10.1016/j.clinthera.2014.10.012

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@article{b2969ddd2d364fa5ad257bebef314341,

title = "Role of Clinical Pharmacology in the Development of Antiplatelet Drugs",

abstract = "This review discusses the role of clinical pharmacology in the development of low-dose aspirin and other antiplatelet agents during the past 30 years, emphasizing the main determinants of several success stories as well as of complete failures in the field.",

keywords = "GPIIb/IIIa blockers, P2Y(12) blockers, PAR-1 antagonists, TP antagonists, aspirin, GPIIb/IIIa blockers, P2Y(12) blockers, PAR-1 antagonists, TP antagonists, aspirin",

author = "Carlo Patrono",

year = "2014",

doi = "10.1016/j.clinthera.2014.10.012",

language = "English",

volume = "36",

pages = "2096--2111",

journal = "Clinical Therapeutics",

issn = "0149-2918",

publisher = "Elsevier Inc.",

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TY - JOUR

T1 - Role of Clinical Pharmacology in the Development of Antiplatelet Drugs

AU - Patrono, Carlo

PY - 2014

Y1 - 2014

N2 - This review discusses the role of clinical pharmacology in the development of low-dose aspirin and other antiplatelet agents during the past 30 years, emphasizing the main determinants of several success stories as well as of complete failures in the field.

AB - This review discusses the role of clinical pharmacology in the development of low-dose aspirin and other antiplatelet agents during the past 30 years, emphasizing the main determinants of several success stories as well as of complete failures in the field.

KW - GPIIb/IIIa blockers

KW - P2Y(12) blockers

KW - PAR-1 antagonists

KW - TP antagonists

KW - aspirin

KW - GPIIb/IIIa blockers

KW - P2Y(12) blockers

KW - PAR-1 antagonists

KW - TP antagonists

KW - aspirin

UR - http://hdl.handle.net/10807/63529

U2 - 10.1016/j.clinthera.2014.10.012

DO - 10.1016/j.clinthera.2014.10.012

M3 - Article

SN - 0149-2918

VL - 36

SP - 2096

EP - 2111

JO - Clinical Therapeutics

JF - Clinical Therapeutics

ER -

Role of Clinical Pharmacology in the Development of Antiplatelet Drugs

Abstract

Keywords

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