Role of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase-3 beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning in isolated human right atria

S Lemoine; L Zhu; G Beauchef; O Lepage; G Babatasi; C Ivascau; Massimo Massetti; P Galera; J Gérard; J. Hanouz

doi:10.1097/ALN.0b013e3181d74f39

Role of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase-3 beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning in isolated human right atria

S Lemoine
, L Zhu
, G Beauchef
, O Lepage
, G Babatasi
, C Ivascau
, Massimo Massetti
, P Galera
, J Gérard
, J. Hanouz

Risultato della ricerca: Contributo in rivista › Articolo

13 Citazioni (Scopus)

Abstract

Desflurane during early reperfusion has been shown to postcondition human myocardium. Whether it involves "reperfusion injury salvage kinase" pathway remains incompletely studied. The authors tested the involvement of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase (GSK)-3beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning.

Lingua originale	Inglese
pagine (da-a)	1355-1363
Numero di pagine	9
Rivista	Anesthesiology
Volume	112
DOI	https://doi.org/10.1097/ALN.0b013e3181d74f39
Stato di pubblicazione	Pubblicato - 2010

Keywords

Atrial Function, Right
Glycogen Synthase Kinase 3
Humans
Isoflurane
Mitochondrial Membrane Transport Proteins
Myocardial Reperfusion Injury
Nitric Oxide Synthase
Ribosomal Protein S6 Kinases, 70-kDa
Time Factors

Accesso al documento

10.1097/ALN.0b013e3181d74f39

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Cita questo

Lemoine, S., Zhu, L., Beauchef, G., Lepage, O., Babatasi, G., Ivascau, C., Massetti, M., Galera, P., Gérard, J., & Hanouz, J. (2010). Role of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase-3 beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning in isolated human right atria. Anesthesiology, 112, 1355-1363. https://doi.org/10.1097/ALN.0b013e3181d74f39

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title = "Role of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase-3 beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning in isolated human right atria",

abstract = "Desflurane during early reperfusion has been shown to postcondition human myocardium. Whether it involves {"}reperfusion injury salvage kinase{"} pathway remains incompletely studied. The authors tested the involvement of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase (GSK)-3beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning.",

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author = "S Lemoine and L Zhu and G Beauchef and O Lepage and G Babatasi and C Ivascau and Massimo Massetti and P Galera and J G{\'e}rard and J. Hanouz",

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doi = "10.1097/ALN.0b013e3181d74f39",

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publisher = "Lippincott Williams and Wilkins",

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Lemoine, S, Zhu, L, Beauchef, G, Lepage, O, Babatasi, G, Ivascau, C, Massetti, M, Galera, P, Gérard, J & Hanouz, J 2010, 'Role of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase-3 beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning in isolated human right atria', Anesthesiology, vol. 112, pagg. 1355-1363. https://doi.org/10.1097/ALN.0b013e3181d74f39

TY - JOUR

T1 - Role of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase-3 beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning in isolated human right atria

AU - Lemoine, S

AU - Zhu, L

AU - Beauchef, G

AU - Lepage, O

AU - Babatasi, G

AU - Ivascau, C

AU - Massetti, Massimo

AU - Galera, P

AU - Gérard, J

AU - Hanouz, J.

PY - 2010

Y1 - 2010

N2 - Desflurane during early reperfusion has been shown to postcondition human myocardium. Whether it involves "reperfusion injury salvage kinase" pathway remains incompletely studied. The authors tested the involvement of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase (GSK)-3beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning.

AB - Desflurane during early reperfusion has been shown to postcondition human myocardium. Whether it involves "reperfusion injury salvage kinase" pathway remains incompletely studied. The authors tested the involvement of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase (GSK)-3beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning.

KW - Atrial Function, Right

KW - Glycogen Synthase Kinase 3

KW - Humans

KW - Isoflurane

KW - Mitochondrial Membrane Transport Proteins

KW - Myocardial Reperfusion Injury

KW - Nitric Oxide Synthase

KW - Ribosomal Protein S6 Kinases, 70-kDa

KW - Time Factors

KW - Atrial Function, Right

KW - Glycogen Synthase Kinase 3

KW - Humans

KW - Isoflurane

KW - Mitochondrial Membrane Transport Proteins

KW - Myocardial Reperfusion Injury

KW - Nitric Oxide Synthase

KW - Ribosomal Protein S6 Kinases, 70-kDa

KW - Time Factors

UR - http://hdl.handle.net/10807/33257

U2 - 10.1097/ALN.0b013e3181d74f39

DO - 10.1097/ALN.0b013e3181d74f39

M3 - Article

SN - 0003-3022

VL - 112

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JO - Anesthesiology

JF - Anesthesiology

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