TY - JOUR
T1 - Role of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase-3 beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning in isolated human right atria
AU - Lemoine, S
AU - Zhu, L
AU - Beauchef, G
AU - Lepage, O
AU - Babatasi, G
AU - Ivascau, C
AU - Massetti, Massimo
AU - Galera, P
AU - Gérard, J
AU - Hanouz, J.
PY - 2010
Y1 - 2010
N2 - Desflurane during early reperfusion has been shown to postcondition human myocardium. Whether it involves "reperfusion injury salvage kinase" pathway remains incompletely studied. The authors tested the involvement of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase (GSK)-3beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning.
AB - Desflurane during early reperfusion has been shown to postcondition human myocardium. Whether it involves "reperfusion injury salvage kinase" pathway remains incompletely studied. The authors tested the involvement of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase (GSK)-3beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning.
KW - Atrial Function, Right
KW - Glycogen Synthase Kinase 3
KW - Humans
KW - Isoflurane
KW - Mitochondrial Membrane Transport Proteins
KW - Myocardial Reperfusion Injury
KW - Nitric Oxide Synthase
KW - Ribosomal Protein S6 Kinases, 70-kDa
KW - Time Factors
KW - Atrial Function, Right
KW - Glycogen Synthase Kinase 3
KW - Humans
KW - Isoflurane
KW - Mitochondrial Membrane Transport Proteins
KW - Myocardial Reperfusion Injury
KW - Nitric Oxide Synthase
KW - Ribosomal Protein S6 Kinases, 70-kDa
KW - Time Factors
UR - http://hdl.handle.net/10807/33257
U2 - 10.1097/ALN.0b013e3181d74f39
DO - 10.1097/ALN.0b013e3181d74f39
M3 - Article
SN - 0003-3022
VL - 112
SP - 1355
EP - 1363
JO - Anesthesiology
JF - Anesthesiology
ER -