Desflurane during early reperfusion has been shown to postcondition human myocardium. Whether it involves "reperfusion injury salvage kinase" pathway remains incompletely studied. The authors tested the involvement of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase (GSK)-3beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning.
- Atrial Function, Right
- Glycogen Synthase Kinase 3
- Mitochondrial Membrane Transport Proteins
- Myocardial Reperfusion Injury
- Nitric Oxide Synthase
- Ribosomal Protein S6 Kinases, 70-kDa
- Time Factors