Role of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase-3 beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning in isolated human right atria

Massimo Massetti, S Lemoine, L Zhu, G Beauchef, O Lepage, G Babatasi, C Ivascau, P Galera, J Gérard, J. Hanouz

Risultato della ricerca: Contributo in rivistaArticolo in rivista

13 Citazioni (Scopus)

Abstract

Desflurane during early reperfusion has been shown to postcondition human myocardium. Whether it involves "reperfusion injury salvage kinase" pathway remains incompletely studied. The authors tested the involvement of 70-kDa ribosomal protein S6 kinase, nitric oxide synthase, glycogen synthase kinase (GSK)-3beta, and mitochondrial permeability transition pore in desflurane-induced postconditioning.
Lingua originaleEnglish
pagine (da-a)1355-1363
Numero di pagine9
RivistaAnesthesiology
Volume112
DOI
Stato di pubblicazionePubblicato - 2010

Keywords

  • Atrial Function, Right
  • Glycogen Synthase Kinase 3
  • Humans
  • Isoflurane
  • Mitochondrial Membrane Transport Proteins
  • Myocardial Reperfusion Injury
  • Nitric Oxide Synthase
  • Ribosomal Protein S6 Kinases, 70-kDa
  • Time Factors

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