Revised upper limb module for spinal muscular atrophy: 12 month changes

Maria Carmela Pera, Giorgia Coratti, Roberto De Sanctis, Marika Pane, Eugenio Maria Mercuri

Risultato della ricerca: Contributo in rivistaArticolo in rivista

19 Citazioni (Scopus)


Abstract INTRODUCTION: The aim of the study was to assess 12 month changes in upper limb function in patients affected by spinal muscular atrophy type 2 and 3. METHODS: Longitudinal 12 month data was collected in 114 patients, 60 type 2 and 54 type 3, using the Revised Upper Limb Module. RESULTS: The 12 month changes ranged between -7 and 9 (mean: -0.41; SD: 2.93). The mean changes were not significantly different between the three spinal muscular atrophy groups (-0.45 in type 2, -0.23 in non-ambulant type 3 and -0.34 in ambulant type 3, p = 0.96) and the relationship between 12 month change and age classes was not significantly different among the three types of SMA patients. DISCUSSION: Our results confirm that the Module explores a wide range of functional abilities and can be used in ambulant and non-ambulant patients of different ages in conjunction with other functional scales. Muscle Nerve 59:426-430, 2019. © 2019 Wiley Periodicals, Inc. KEYWORDS: Functional assessment; Longitudinal Data; Neuromuscular disorders; Outcome measures; Spinal Muscular Atrophy; Upper limb
Lingua originaleEnglish
pagine (da-a)426-430
Numero di pagine5
Stato di pubblicazionePubblicato - 2019




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