Retinoic acid and arsenic trioxide for acute promyelocytic leukemia

F. Lo-Coco, G. Avvisati, M. Vignetti, C. Thiede, S. M. Orlando, S. Iacobelli, F. Ferrara, P. Fazi, L. Cicconi, E. Di Bona, G. Specchia, Simona Sica, M. Divona, A. Levis, W. Fiedler, E. Cerqui, M. Breccia, G. Fioritoni, H. R. Salih, M. CazzolaL. Melillo, A. M. Carella, C. H. Brandts, E. Morra, M. Von Lilienfeld-Toal, B. Hertenstein, M. Wattad, M. Lübbert, M. Hänel, N. Schmitz, H. Link, M. G. Kropp, A. Rambaldi, G. La Nasa, M. Luppi, F. Ciceri, O. Finizio, A. Venditti, F. Fabbiano, K. Döhner, M. Sauer, A. Ganser, S. Amadori, F. Mandelli, H. Döhner, G. Ehninger, R. F. Schlenk, U. Platzbecker

Risultato della ricerca: Contributo in rivistaArticolo in rivista

819 Citazioni (Scopus)

Abstract

All-trans retinoic acid (ATRA) with chemotherapy is the standard of care for acute promyelocytic leukemia (APL), resulting in cure rates exceeding 80%. Pilot studies of treatment with arsenic trioxide with or without ATRA have shown high efficacy and reduced hematologic toxicity.
Lingua originaleEnglish
pagine (da-a)111-121
Numero di pagine11
RivistaNew England Journal of Medicine
Volume369
DOI
Stato di pubblicazionePubblicato - 2013

Keywords

  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols
  • Arsenicals
  • Consolidation Chemotherapy
  • Disease-Free Survival
  • Female
  • Humans
  • Induction Chemotherapy
  • Leukemia, Promyelocytic, Acute
  • Maintenance Chemotherapy
  • Male
  • Middle Aged
  • Neutropenia
  • Oxides
  • Thrombocytopenia
  • Tretinoin
  • Young Adult

Fingerprint

Entra nei temi di ricerca di 'Retinoic acid and arsenic trioxide for acute promyelocytic leukemia'. Insieme formano una fingerprint unica.

Cita questo