Resectability and Vascular Management of Retroperitoneal Gynecological Malignancies: A Large Single-institution Case-Series

Giovanni Tinelli, Serena Cappuccio, Ezio Parente, Anna Fagotti, Valerio Gallotta, Carmine Conte, Barbara Costantini, Salvatore Gueli Alletti, Giovanni Scambia, Giuseppe Vizzielli

Risultato della ricerca: Contributo in rivistaArticolo

11 Citazioni (Scopus)

Abstract

ACKGROUND/AIM: To report on morbidity and oncological outcomes in a consecutive series of gynecological malignancies involving the vascular district. PATIENTS AND METHODS: We retrospectively evaluated a consecutive series between 1/2015 and 1/2017 with suspicious gynecological malignancies involving the vascular district. Peri-operative data and survival rates were computed. RESULTS: Eight-hundred-four women with gynecological malignancies were admitted for major oncologic surgery during the study period, and among them, 50 cases (6.2%) showed vascular involvement. Twenty-seven and 23 patients were submitted to minor and major vascular procedures, respectively. R0 resection was achieved in 44 patients. There were no perioperative mortalities. Major postoperative complications occurred in 6 patients (12.0%). The 2-year disease free survival (DFS) was 67% if R0 resection was achieved. In patients with positive pathological margins (n=2), the 2-year DFS was 33%. CONCLUSION: Vascular procedures can be safely performed with a proper pre-operative planning and may not be an impediment to major gynecological oncological surgery.
Lingua originaleInglese
pagine (da-a)6899-6906
Numero di pagine8
RivistaAnticancer Research
Volume37
DOI
Stato di pubblicazionePubblicato - 2017

Keywords

  • Abscess
  • Adult
  • Aged
  • Female
  • Genital Neoplasms, Female
  • Humans
  • Kaplan-Meier Estimate
  • Middle Aged
  • Pelvic Infection
  • Postoperative Complications
  • Retroperitoneal Neoplasms
  • Retrospective Studies
  • Vascular Surgical Procedures
  • Vascular resection
  • Young Adult
  • gynecological malignancies
  • post-operative complications

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