Reliability of the Performance of Upper Limb assessment in Duchenne muscular dystrophy

Marika Pane; Eugenio Maria Mercuri; Roberto De Sanctis; Flaviana Bianco; Serena Sivo; Adele D'Amico; Elena S. Mazzone; Lavinia Fanelli; Sonia Messina; Roberta Battini; Marianna Scutifero; Roberta Petillo; Silvia Frosini; Roberta Scalise; Gianluca Vita; Claudio Bruno; Marina Pedemonte; Tiziana Mongini; Elena Pegoraro; Francesca Brustia; Alice Gardani; Angela Berardinelli; Valentina Lanzillotta; Emanuela Viggiano; Filippo Cavallaro; Maria Sframeli; Luca Bello; Andrea Barp; Serena Bonfiglio; Enrica Rolle; Giulia Colia; Michela Catteruccia; Concetta Palermo; Grazia D'Angelo; Antonella Pini; Elena Iotti; Ksenija Gorni; Giovanni Baranello; Lucia Morandi; Enrico Bertini; Luisa Politano; Mariapia Sormani; Eugenio Mercuri

doi:10.1016/j.nmd.2013.11.014

Reliability of the Performance of Upper Limb assessment in Duchenne muscular dystrophy

Marika Pane, Eugenio Maria Mercuri, Roberto De Sanctis, Flaviana Bianco, Serena Sivo, Adele D'Amico, Elena S. Mazzone, Lavinia Fanelli, Sonia Messina, Roberta Battini, Marianna Scutifero, Roberta Petillo, Silvia Frosini, Roberta Scalise, Gianluca Vita, Claudio Bruno, Marina Pedemonte, Tiziana Mongini, Elena Pegoraro, Francesca BrustiaAlice Gardani, Angela Berardinelli, Valentina Lanzillotta, Emanuela Viggiano, Filippo Cavallaro, Maria Sframeli, Luca Bello, Andrea Barp, Serena Bonfiglio, Enrica Rolle, Giulia Colia, Michela Catteruccia, Concetta Palermo, Grazia D'Angelo, Antonella Pini, Elena Iotti, Ksenija Gorni, Giovanni Baranello, Lucia Morandi, Enrico Bertini, Luisa Politano, Mariapia Sormani, Eugenio Mercuri

Risultato della ricerca: Contributo in rivista › Articolo in rivista

59 Citazioni (Scopus)

Abstract

The Performance of Upper Limb was specifically designed to assess upper limb function in Duchenne muscular dystrophy. The aim of this study was to assess (1) a cohort of typically developing children from the age of 3years onwards in order to identify the age when the activities assessed in the individual items are consistently achieved, and (2) a cohort of 322 Duchenne children and young adults to establish the range of findings at different ages. We collected normative data for the scale validation on 277 typically developing subjects from 3 to 25years old. A full score was consistently achieved by the age of 5years. In the Duchenne cohort there was early involvement of the proximal muscles and a proximal to distal progressive involvement. The scale was capable of measuring small distal movements, related to activities of daily living, even in the oldest and weakest patients. Our data suggest that the assessment can be reliably used in both ambulant and non ambulant Duchenne patients in a multicentric setting and could therefore be considered as an outcome measure for future trials.

Lingua originale	English
pagine (da-a)	201-206
Numero di pagine	6
Rivista	Neuromuscular Disorders
Volume	24
DOI	https://doi.org/10.1016/j.nmd.2013.11.014
Stato di pubblicazione	Pubblicato - 2014

Keywords

Adolescent
Adult
Child
Child, Preschool
Disease Progression
Duchenne muscular dystrophy
Humans
Male
Muscular Dystrophy, Duchenne
Symptom Assessment
Upper Extremity
Upper limb
Young Adult

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10.1016/j.nmd.2013.11.014

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Pane, M., Mercuri, E. M., De Sanctis, R., Bianco, F., Sivo, S., D'Amico, A., Mazzone, E. S., Fanelli, L., Messina, S., Battini, R., Scutifero, M., Petillo, R., Frosini, S., Scalise, R., Vita, G., Bruno, C., Pedemonte, M., Mongini, T., Pegoraro, E., ... Mercuri, E. (2014). Reliability of the Performance of Upper Limb assessment in Duchenne muscular dystrophy. Neuromuscular Disorders, 24, 201-206. https://doi.org/10.1016/j.nmd.2013.11.014

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title = "Reliability of the Performance of Upper Limb assessment in Duchenne muscular dystrophy",

abstract = "The Performance of Upper Limb was specifically designed to assess upper limb function in Duchenne muscular dystrophy. The aim of this study was to assess (1) a cohort of typically developing children from the age of 3years onwards in order to identify the age when the activities assessed in the individual items are consistently achieved, and (2) a cohort of 322 Duchenne children and young adults to establish the range of findings at different ages. We collected normative data for the scale validation on 277 typically developing subjects from 3 to 25years old. A full score was consistently achieved by the age of 5years. In the Duchenne cohort there was early involvement of the proximal muscles and a proximal to distal progressive involvement. The scale was capable of measuring small distal movements, related to activities of daily living, even in the oldest and weakest patients. Our data suggest that the assessment can be reliably used in both ambulant and non ambulant Duchenne patients in a multicentric setting and could therefore be considered as an outcome measure for future trials.",

keywords = "Adolescent, Adult, Child, Child, Preschool, Disease Progression, Duchenne muscular dystrophy, Humans, Male, Muscular Dystrophy, Duchenne, Symptom Assessment, Upper Extremity, Upper limb, Young Adult, Adolescent, Adult, Child, Child, Preschool, Disease Progression, Duchenne muscular dystrophy, Humans, Male, Muscular Dystrophy, Duchenne, Symptom Assessment, Upper Extremity, Upper limb, Young Adult",

author = "Marika Pane and Mercuri, {Eugenio Maria} and {De Sanctis}, Roberto and Flaviana Bianco and Serena Sivo and Adele D'Amico and Mazzone, {Elena S.} and Lavinia Fanelli and Sonia Messina and Roberta Battini and Marianna Scutifero and Roberta Petillo and Silvia Frosini and Roberta Scalise and Gianluca Vita and Claudio Bruno and Marina Pedemonte and Tiziana Mongini and Elena Pegoraro and Francesca Brustia and Alice Gardani and Angela Berardinelli and Valentina Lanzillotta and Emanuela Viggiano and Filippo Cavallaro and Maria Sframeli and Luca Bello and Andrea Barp and Serena Bonfiglio and Enrica Rolle and Giulia Colia and Michela Catteruccia and Concetta Palermo and Grazia D'Angelo and Antonella Pini and Elena Iotti and Ksenija Gorni and Giovanni Baranello and Lucia Morandi and Enrico Bertini and Luisa Politano and Mariapia Sormani and Eugenio Mercuri",

year = "2014",

doi = "10.1016/j.nmd.2013.11.014",

language = "English",

volume = "24",

pages = "201--206",

journal = "Neuromuscular Disorders",

issn = "0960-8966",

publisher = "Elsevier Science Limited:Oxford Fulfillment Center, PO Box 800, Kidlington Oxford OX5 1DX United Kingdom:011 44 1865 843000, 011 44 1865 843699, EMAIL: asianfo@elsevier.com, tcb@elsevier.co.UK, INTERNET: http://www.elsevier.com, http://www.elsevier.com/locate/shpsa/, Fax: 011 44 1865 843010",

}

Pane, M , Mercuri, EM, De Sanctis, R, Bianco, F, Sivo, S, D'Amico, A, Mazzone, ES, Fanelli, L, Messina, S, Battini, R, Scutifero, M, Petillo, R, Frosini, S, Scalise, R, Vita, G, Bruno, C, Pedemonte, M, Mongini, T, Pegoraro, E, Brustia, F, Gardani, A, Berardinelli, A, Lanzillotta, V, Viggiano, E, Cavallaro, F, Sframeli, M, Bello, L, Barp, A, Bonfiglio, S, Rolle, E, Colia, G, Catteruccia, M, Palermo, C, D'Angelo, G, Pini, A, Iotti, E, Gorni, K, Baranello, G, Morandi, L, Bertini, E, Politano, L, Sormani, M & Mercuri, E 2014, 'Reliability of the Performance of Upper Limb assessment in Duchenne muscular dystrophy', Neuromuscular Disorders, vol. 24, pagg. 201-206. https://doi.org/10.1016/j.nmd.2013.11.014

TY - JOUR

T1 - Reliability of the Performance of Upper Limb assessment in Duchenne muscular dystrophy

AU - Pane, Marika

AU - Mercuri, Eugenio Maria

AU - De Sanctis, Roberto

AU - Bianco, Flaviana

AU - Sivo, Serena

AU - D'Amico, Adele

AU - Mazzone, Elena S.

AU - Fanelli, Lavinia

AU - Messina, Sonia

AU - Battini, Roberta

AU - Scutifero, Marianna

AU - Petillo, Roberta

AU - Frosini, Silvia

AU - Scalise, Roberta

AU - Vita, Gianluca

AU - Bruno, Claudio

AU - Pedemonte, Marina

AU - Mongini, Tiziana

AU - Pegoraro, Elena

AU - Brustia, Francesca

AU - Gardani, Alice

AU - Berardinelli, Angela

AU - Lanzillotta, Valentina

AU - Viggiano, Emanuela

AU - Cavallaro, Filippo

AU - Sframeli, Maria

AU - Bello, Luca

AU - Barp, Andrea

AU - Bonfiglio, Serena

AU - Rolle, Enrica

AU - Colia, Giulia

AU - Catteruccia, Michela

AU - Palermo, Concetta

AU - D'Angelo, Grazia

AU - Pini, Antonella

AU - Iotti, Elena

AU - Gorni, Ksenija

AU - Baranello, Giovanni

AU - Morandi, Lucia

AU - Bertini, Enrico

AU - Politano, Luisa

AU - Sormani, Mariapia

AU - Mercuri, Eugenio

PY - 2014

Y1 - 2014

N2 - The Performance of Upper Limb was specifically designed to assess upper limb function in Duchenne muscular dystrophy. The aim of this study was to assess (1) a cohort of typically developing children from the age of 3years onwards in order to identify the age when the activities assessed in the individual items are consistently achieved, and (2) a cohort of 322 Duchenne children and young adults to establish the range of findings at different ages. We collected normative data for the scale validation on 277 typically developing subjects from 3 to 25years old. A full score was consistently achieved by the age of 5years. In the Duchenne cohort there was early involvement of the proximal muscles and a proximal to distal progressive involvement. The scale was capable of measuring small distal movements, related to activities of daily living, even in the oldest and weakest patients. Our data suggest that the assessment can be reliably used in both ambulant and non ambulant Duchenne patients in a multicentric setting and could therefore be considered as an outcome measure for future trials.

AB - The Performance of Upper Limb was specifically designed to assess upper limb function in Duchenne muscular dystrophy. The aim of this study was to assess (1) a cohort of typically developing children from the age of 3years onwards in order to identify the age when the activities assessed in the individual items are consistently achieved, and (2) a cohort of 322 Duchenne children and young adults to establish the range of findings at different ages. We collected normative data for the scale validation on 277 typically developing subjects from 3 to 25years old. A full score was consistently achieved by the age of 5years. In the Duchenne cohort there was early involvement of the proximal muscles and a proximal to distal progressive involvement. The scale was capable of measuring small distal movements, related to activities of daily living, even in the oldest and weakest patients. Our data suggest that the assessment can be reliably used in both ambulant and non ambulant Duchenne patients in a multicentric setting and could therefore be considered as an outcome measure for future trials.

KW - Adolescent

KW - Adult

KW - Child

KW - Child, Preschool

KW - Disease Progression

KW - Duchenne muscular dystrophy

KW - Humans

KW - Male

KW - Muscular Dystrophy, Duchenne

KW - Symptom Assessment

KW - Upper Extremity

KW - Upper limb

KW - Young Adult

KW - Adolescent

KW - Adult

KW - Child

KW - Child, Preschool

KW - Disease Progression

KW - Duchenne muscular dystrophy

KW - Humans

KW - Male

KW - Muscular Dystrophy, Duchenne

KW - Symptom Assessment

KW - Upper Extremity

KW - Upper limb

KW - Young Adult

UR - http://hdl.handle.net/10807/65139

U2 - 10.1016/j.nmd.2013.11.014

DO - 10.1016/j.nmd.2013.11.014

M3 - Article

VL - 24

SP - 201

EP - 206

JO - Neuromuscular Disorders

JF - Neuromuscular Disorders

SN - 0960-8966

ER -

Reliability of the Performance of Upper Limb assessment in Duchenne muscular dystrophy

Abstract

Keywords

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