Abstract
A woman affected by multiple cranial nerve palsy developed several episodes of total insomnia and respiratory crises resulting from central breathing depression associated with dysautonomic symptoms. Oligoclonal IgG bands were present in her cerebrospinal fluid, and immunohistochemistry showed increased binding of serum and cerebrospinal fluid on gamma-aminobutyric acid-ergic, synapse-rich neuronal cells. Immunosuppressive treatment and plasma exchange were followed by clinical improvement, with restoration of sleep architecture and disappearance of respiratory crises, suggesting autoimmune pathogenesis of the syndrome.
Lingua originale | English |
---|---|
pagine (da-a) | 668-671 |
Numero di pagine | 4 |
Rivista | Annals of Neurology |
Volume | 50 |
Stato di pubblicazione | Pubblicato - 2001 |
Keywords
- Autoimmune Diseases
- Autonomic Nervous System Diseases
- Cranial Nerve Diseases
- Electroencephalography
- Immunosuppressive Agents
- Plasma Exchange
- Polysomnography
- Respiratory Insufficiency
- Sleep Initiation and Maintenance Disorders
- Syndrome
- Voice Disorders