Relapsing-remitting autoimmune agrypnia

Giacomo Della Marca, Massimiliano Mirabella, Anna Paola Batocchi, Giovanni Frisullo, Marcella Caggiula, Gf Mennuni, Pa Tonali

Risultato della ricerca: Contributo in rivistaArticolo in rivista

14 Citazioni (Scopus)

Abstract

A woman affected by multiple cranial nerve palsy developed several episodes of total insomnia and respiratory crises resulting from central breathing depression associated with dysautonomic symptoms. Oligoclonal IgG bands were present in her cerebrospinal fluid, and immunohistochemistry showed increased binding of serum and cerebrospinal fluid on gamma-aminobutyric acid-ergic, synapse-rich neuronal cells. Immunosuppressive treatment and plasma exchange were followed by clinical improvement, with restoration of sleep architecture and disappearance of respiratory crises, suggesting autoimmune pathogenesis of the syndrome.
Lingua originaleEnglish
pagine (da-a)668-671
Numero di pagine4
RivistaAnnals of Neurology
Volume50
Stato di pubblicazionePubblicato - 2001

Keywords

  • Autoimmune Diseases
  • Autonomic Nervous System Diseases
  • Cranial Nerve Diseases
  • Electroencephalography
  • Immunosuppressive Agents
  • Plasma Exchange
  • Polysomnography
  • Respiratory Insufficiency
  • Sleep Initiation and Maintenance Disorders
  • Syndrome
  • Voice Disorders

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