Reelin in human Glioblastoma and in cancer stem cells isolated from tumor and peritumor tissue

Alessio D'Alessio, Bianca Maria Scicchitano, Filippo Biamonte, Gina Lama, Giulio Maira, Gigliola Sica, Al Vescovi

Risultato della ricerca: Contributo in libroContributo a convegno

Abstract

Reelin is a large secreted extracellular matrix glycoprotein which contributes to positioning, migration and laminar organization of several central nervous system structures during neurodevelopment. Recent studies reported the expression of Reelin and its intracellular adapter protein DAB-1 in neuroblastoma, where it is involved in cell motility and invasiveness. The aim of this study was to investigate the expression of Reelin in both tumor and peritumor tissue derived from glioblastoma (GBM), and in cancer stem cells (CSC) isolated from both tumor (GCSC) and peritumor tissue (PCSC).
Lingua originaleEnglish
Titolo della pubblicazione ospiteInternational Neuroscience Congress
Pagine03
Numero di pagine1
Stato di pubblicazionePubblicato - 2014
EventoInternational Neuroscience Congress - Roma
Durata: 12 giu 201413 giu 2014

Convegno

ConvegnoInternational Neuroscience Congress
CittàRoma
Periodo12/6/1413/6/14

Keywords

  • Glioblastoma
  • Reelin

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