TY - JOUR
T1 - Recent Advances in Nanotechnology for the Treatment of Melanoma.
AU - Cassano, Roberta
AU - Cuconato, Massimo
AU - Calviello, Gabriella
AU - Serini, Simona
AU - Trombino, Sonia
PY - 2021
Y1 - 2021
N2 - Melanoma is one of the most aggressive forms of skin cancer, with few possibilities for therapeutic approaches, due to its multi-drug resistance and, consequently, low survival rate for patients. Conventional therapies for treatment melanoma include radiotherapy, chemotherapy, targeted therapy, and immunotherapy, which have various side effects. For this reason, in recent years, pharmaceutical and biomedical research has focused on new sito-specific alternative therapeutic strategies. In this regard, nanotechnology offers numerous benefits which could improve the life expectancy of melanoma patients with very low adverse effects. This review aims to examine the latest advances
in nanotechnology as an innovative strategy for treating melanoma. In particular, the use of different types of nanoparticles, such as vesicles, polymers, metal-based, carbon nanotubes, dendrimers, solid lipid, microneedles, and their combination with immunotherapies and vaccines will be discussed.
AB - Melanoma is one of the most aggressive forms of skin cancer, with few possibilities for therapeutic approaches, due to its multi-drug resistance and, consequently, low survival rate for patients. Conventional therapies for treatment melanoma include radiotherapy, chemotherapy, targeted therapy, and immunotherapy, which have various side effects. For this reason, in recent years, pharmaceutical and biomedical research has focused on new sito-specific alternative therapeutic strategies. In this regard, nanotechnology offers numerous benefits which could improve the life expectancy of melanoma patients with very low adverse effects. This review aims to examine the latest advances
in nanotechnology as an innovative strategy for treating melanoma. In particular, the use of different types of nanoparticles, such as vesicles, polymers, metal-based, carbon nanotubes, dendrimers, solid lipid, microneedles, and their combination with immunotherapies and vaccines will be discussed.
KW - immunotherapy
KW - melanoma
KW - nanomaterials
KW - nanotechnology
KW - polymers
KW - target therapy
KW - immunotherapy
KW - melanoma
KW - nanomaterials
KW - nanotechnology
KW - polymers
KW - target therapy
UR - http://hdl.handle.net/10807/169522
U2 - 10.3390/molecules26040785
DO - 10.3390/molecules26040785
M3 - Article
SN - 1420-3049
VL - 2021
SP - 785-N/A
JO - Molecules
JF - Molecules
ER -