Reassessing IVIg therapy in chronic inflammatory demyelinating polyradiculoneuropathy during COVID-19: a chance to verify the need for chronic maintenance therapy

Mario Sabatelli, Marina Romozzi, Paolo Gaetano Bisogni, Marco Luigetti

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

The outbreak of a severe acute respiratory syndrome caused by a novel coronavirus (COVID-19), has raised health concerns for patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), who are frequently on long-term immunotherapies. Treatment with IVIg does not increase the risk of contracting COVID-19, and the IVIg administration may have a protective role. However, infusions can expose patients to an increased risk of contracting SARS-CoV-2 due to repeated access to Health Facilities. In this report we analyzed the short-term follow-up of CIDP patients who modified their chronic IVIg therapy during pandemic. About half of CIDP patients regularly treated with IVIg tried to stop treatment and about 10% shifted to SCIg. Forty-two percent of the patients who stopped the treatment reported a clinical deterioration after suspension and had to restart IVIg. This study demonstrated that in selected cases it is possible to successfully stop the chronic IVIg treatment, even in patients who have been treated for several years.
Lingua originaleEnglish
pagine (da-a)787-789
Numero di pagine3
RivistaNeurological Sciences
Volume42
DOI
Stato di pubblicazionePubblicato - 2021

Keywords

  • CIDP
  • COVID-19
  • IVIg
  • Pandemic
  • SCIg
  • Adult
  • Aged
  • Female
  • Humans
  • Immunoglobulins, Intravenous
  • Male
  • Middle Aged
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
  • SARS-CoV-2

Fingerprint Entra nei temi di ricerca di 'Reassessing IVIg therapy in chronic inflammatory demyelinating polyradiculoneuropathy during COVID-19: a chance to verify the need for chronic maintenance therapy'. Insieme formano una fingerprint unica.

Cita questo