TY - JOUR
T1 - Reactive lymphoid hyperplasia of liver mimicking late ovarian cancer recurrence: Case report and literature review
AU - Marchetti, Claudia
AU - Manci, Natalina
AU - Di Maurizio, Marco
AU - Di Tucci, Chiara
AU - Burratti, Moira
AU - Iuliano, Marialetizia
AU - Giorgini, Margherita
AU - Salerno, Laura
AU - Benedetti Panici, Pierluigi
PY - 2011
Y1 - 2011
N2 - Reactive lymphoid hyperplasia (RLH) is a rare, benign, lymphocytic tumour-like lesion reported in various organs. It has been previously identified in 18 cases in the English-language literature, but only 5 of them were related to oncological disease. No previous cases have been described of RLH occurring in ovarian cancer patients. We describe a case of hepatic RLH which developed in a patient treated for ovarian cancer 11 years previously. Radiological features on computed tomography (CT) scan and PET-CT (positron emission tomography-computed tomography) were strongly suggestive of oncological disease, in contrast to magnetic resonance imaging (MRI); the volume increment of the nodular lesion and the rise in carbohydrate antigen 125 corroborated the hypothesis of malignancy. The patient was subjected to resection of the 7th segment of the liver and the final histological report showed RLH. RLH should be considered in the presence of hepatic lesions in suspected ovarian cancer recurrence. Imaging techniques should be thoroughly investigated to exclude tumor recurrence promptly, in order to avoid unnecessary surgery. © 2011 Japan Society of Clinical Oncology.
AB - Reactive lymphoid hyperplasia (RLH) is a rare, benign, lymphocytic tumour-like lesion reported in various organs. It has been previously identified in 18 cases in the English-language literature, but only 5 of them were related to oncological disease. No previous cases have been described of RLH occurring in ovarian cancer patients. We describe a case of hepatic RLH which developed in a patient treated for ovarian cancer 11 years previously. Radiological features on computed tomography (CT) scan and PET-CT (positron emission tomography-computed tomography) were strongly suggestive of oncological disease, in contrast to magnetic resonance imaging (MRI); the volume increment of the nodular lesion and the rise in carbohydrate antigen 125 corroborated the hypothesis of malignancy. The patient was subjected to resection of the 7th segment of the liver and the final histological report showed RLH. RLH should be considered in the presence of hepatic lesions in suspected ovarian cancer recurrence. Imaging techniques should be thoroughly investigated to exclude tumor recurrence promptly, in order to avoid unnecessary surgery. © 2011 Japan Society of Clinical Oncology.
KW - Liver
KW - Ovarian cancer
KW - PET-CT
KW - Reactive lymphoid hyperplasia
KW - Recurrence
KW - Liver
KW - Ovarian cancer
KW - PET-CT
KW - Reactive lymphoid hyperplasia
KW - Recurrence
UR - http://hdl.handle.net/10807/205132
U2 - 10.1007/s10147-011-0191-9
DO - 10.1007/s10147-011-0191-9
M3 - Article
SN - 1341-9625
VL - 16
SP - 714
EP - 717
JO - International Journal of Clinical Oncology
JF - International Journal of Clinical Oncology
ER -