Re: Amplitude ratio of ulnar sensory nerve action potentials in segmental conduction study.

Luca Padua, Pietro Caliandro, Costanza Pazzaglia, Giuseppe Granata, Pietro Attilio Tonali

Risultato della ricerca: Contributo in rivistaArticolo in rivista

1 Citazioni (Scopus)

Abstract

The Italian CMT study group performed a multicentre, multidimensional, longitudinal 2-year follow-up study using validated measurements of neurological impairment, disability and quality of life. The aim of the study was to evaluate the natural history of clinical features, disability and QoL in patients with CMT1A. On clinical examination, CMT1A patients showed a significant reduction in muscle strength and sensory function during the 2-year follow-up period. However, there was no worsening of QoL or disability, nor was depression observed. The discrepancy between the evolution of clinical features and the evolution of QoL and disability may be due to the development of compensatory strategies that help patients cope with the slow progression of the disease. Our observations provide information which may be useful when designing clinical trials in CMT.
Lingua originaleEnglish
pagine (da-a)1053-1054
Numero di pagine2
RivistaAMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
Volume87
DOI
Stato di pubblicazionePubblicato - 2008

Keywords

  • segmental conduction study

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