Radiomics and radiogenomics in ovarian cancer: a literature review

S. Nougaret, Cathal Mccague, Hichem Tibermacine, Hebert Alberto Vargas, Stefania Rizzo, E. Sala, Evis Sala

Risultato della ricerca: Contributo in rivistaArticolo in rivista


Ovarian cancer remains one of the most lethal gynecological cancers in the world despite extensive progress in the areas of chemotherapy and surgery. Many studies have postulated that this is because of the profound heterogeneity that underpins response to therapy and prognosis. Standard imaging evaluation using CT or MRI does not take into account this tumoral heterogeneity especially in advanced stages with peritoneal carcinomatosis. As such, newly emergent fields in the assessment of tumor heterogeneity have been proposed using radiomics to evaluate the whole tumor burden heterogeneity as opposed to single biopsy sampling. This review provides an overview of radiomics, radiogenomics, and proteomics and examines the use of these newly emergent fields in assessing tumor heterogeneity and its implications in ovarian cancer.
Lingua originaleEnglish
pagine (da-a)2308-2322
Numero di pagine15
RivistaAbdominal Radiology
Stato di pubblicazionePubblicato - 2020


  • Ovarian cancer
  • Proteomics
  • Radiogenomics
  • Radiomics


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