Radial Artery as a Coronary Artery Bypass Conduit: 20-Year Results

Mario Fulvio Luigi Gaudino, Paolo Tondi, Umberto Benedetto, Valentina Milazzo, Roberto Antonio Flore, Franco Glieca, Francesca Romana Ponziani, Nicola Luciani, Leonard N. Girardi, Filippo Crea, Massimo Massetti

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

50 Citazioni (Scopus)


BACKGROUND: There is a lack of evidence for the choice of the second conduit in coronary surgery. The radial artery (RA) is a possible option, but few data on very-long-term outcomes exist. OBJECTIVES: This study describes 20-year results of RA grafts used for coronary artery bypass grafting and the effects of RA removal on forearm circulation. METHODS: We report the results of the prospective 20-year follow-up of the first 100 consecutive patients who received the RA as a coronary bypass conduit at our institution. RESULTS: Follow-up was 100% complete. There were 64 deaths, 23 (35.9%) from cardiovascular causes. Kaplan-Meier 20-year survival was 31%. Of the 36 survivors, 33 (91.6%) underwent RA graft control at a mean of 19.0 ± 2.5 years after surgery. The RA was found to be patent in 24 cases (84.8% patency). In the overall population, probability of graft failure at 20 years was 19.0 ± 0.2% for the left internal thoracic artery (ITA), 25.0 ± 0.2% for the RA, and 55.0 ± 0.2% for the saphenous vein (p = 0.002 for RA vs. saphenous vein, 0.11 for RA vs. ITA, and p < 0.001 for ITA vs. saphenous vein). Target vessel stenosis >90%, but not location of distal anastomosis, significantly influenced long-term RA graft patency. No patients reported hand or forearm symptoms. The ulnar artery diameter was increased in the operated arm (2.44 ± 0.43 mm vs. 2.01 ± 0.47 mm; p < 0.05) and correlated with the peak systolic velocity of the second palmar digital artery (Pearson coefficient: 0.621; p < 0.05). CONCLUSIONS: The 20-year patency rate of RA grafts is good, and not inferior to the ITA, especially when the conduit is used to graft a vessel with >90% stenosis. RA harvesting does not lead to hand or forearm symptoms, even at a very-long-term follow-up.
Lingua originaleEnglish
pagine (da-a)603-10-610
Numero di pagine8
RivistaJournal of the American College of Cardiology
Stato di pubblicazionePubblicato - 2016


  • angiography
  • follow-up studies
  • internal thoracic artery
  • prospective studies
  • saphenous vein


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