Quetiapine as add-on treatment for Bipolar I Disorder with comorbid compulsive buying and physical exercise addiction

Gino Pozzi, Luigi Janiri, Marco Di Nicola, Giovanni Martinotti, Marianna Mazza, Daniela Tedeschi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

13 Citazioni (Scopus)

Abstract

Quetiapine is a second generation antipsychotic that shows affinity for various neurotransmitter receptors: specifically the D1 and D2 dopamine receptor, the alpha-1 and alpha-2 adrenergic receptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. In the bipolar spectrum disorders quetiapine is approved for the treatment of acute manic and mixed episodes associated with bipolar I disorder. It is also approved for the treatment of acute bipolar depressive episodes and as adjunctive maintenance therapy of bipolar I disorder with lithium or valproate. In a previous study we reported the high frequency of association between bipolar disorder and behavioural addictions and the correlation with high level of impulsivity and specific temperamental and character dimensions. We underlined that the assessment of behavioural addictions in bipolar disorder patients may have a direct impact on the choice of pharmacological and psycho-educative interventions aimed at reducing harmful behaviours and the risk of relapses. The present case report deals with the potential use of quetiapine as add-on treatment for bipolar I disorder with comorbid compulsive buying and physical exercise addiction.
Lingua originaleEnglish
pagine (da-a)713-714
Numero di pagine2
RivistaPROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
Stato di pubblicazionePubblicato - 2010

Keywords

  • bipolar disorder
  • compulsive buying
  • physical exercise addiction
  • quetiapine

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