8 Citazioni (Scopus)


The aim of the study was to quantitatively compare the scintigraphic images of the thyroid and abnormal parathyroid glands obtained with technetium-99m tetrofosmin and thallium-201 in patients with hyperparathyroidism. Forty-six patients with hyperparathyroidism underwent (201)Tl (74 MBq), (99m)Tc-pertechnetate (74 MBq) and (99m)Tc-tetrofosmin (555-740 MBq) scintigraphy in a single session. Image analysis included the computation of the thyroid/background ratio in the whole study population and the parathyroid/background ratio, parathyroid/thyroid ratio and diagnostic sensitivity in 17 patients who underwent parathyroid surgery. The pertechnetate subtraction technique was used. (201)Tl and (99m)Tc-tetrofosmin showed a similar thyroid/background ratio (1.79+/-0.41 and 1.81+/-0. 47, respectively, P=NS); however, (99m)Tc-tetrofosmin showed a higher parathyroid/background ratio than (201)Tl (2.06+/-0.54 vs 1. 79+/- 0.50, P=0.007). Despite the superior quality of (99m)Tc-tetrofosmin images, both tracers showed identical sensitivity in detecting enlarged parathyroid glands in patients with primary hyperparathyroidism (89%) and in those with secondary hyperparathyroidism (50%).
Lingua originaleEnglish
pagine (da-a)907-911
Numero di pagine5
RivistaEuropean Journal Of Nuclear Medicine
Stato di pubblicazionePubblicato - 1999


  • Adenoma
  • Female
  • Humans
  • Hyperparathyroidism
  • Hyperparathyroidism, Secondary
  • Male
  • Organophosphorus Compounds
  • Organotechnetium Compounds
  • Parathyroid Glands
  • Parathyroid Neoplasms
  • Radiopharmaceuticals
  • Sensitivity and Specificity
  • Sodium Pertechnetate Tc 99m
  • Thallium Radioisotopes
  • Thyroid Gland

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