Quantification of the determinants of arterial hypoxemia in critically ill patients

Ivo Giovannini, Giuseppe Boldrini, Gabriele Sganga, Gian Carlo Castiglioni, Marco Castagneto

Risultato della ricerca: Contributo in rivistaArticolo in rivista

13 Citazioni (Scopus)


A quantification of the determinants of arterial hypoxemia was performed in 376 cardiorespiratory measurements obtained from 180 critically ill patients. Statistical analysis showed that pulmonary venous admixture (Qsp/Qt) could explain only 48% of the PaO2 variability in the sample of measurements taken (r2 = 0.48), while the effect of central venous O2 tension (PVO2) brought the total explained PaO2 variability up to 82% (total r2 = 0.82). These findings imply that pulmonary function is not the only determinant of PaO2; the PVO2-mediated effect of other cardiovascular and metabolic determinants must be recognized in the clinical setting.
Lingua originaleEnglish
pagine (da-a)644-645
Numero di pagine2
RivistaCritical Care Medicine
Stato di pubblicazionePubblicato - 1983


  • Anoxia
  • Cardiac Output
  • Humans
  • Oxygen
  • Oxygen Consumption
  • Partial Pressure
  • Postoperative Complications
  • Pulmonary Gas Exchange
  • Sepsis


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