Pulmonary embolism in a stroke patient after systemic thrombolysis: clinical decisions and literature review

Giacomo Della Marca, Aldobrando Broccolini, Cesare Colosimo, Fabio Pilato, Rosalinda Calandrelli, Paolo Profice, Giuseppe Bello, Maria Grazia Bocci, Marisa Distefano, Paolo Maria Rossini

Risultato della ricerca: Contributo in rivistaArticolo in rivista

2 Citazioni (Scopus)

Abstract

Pulmonary embolism can be a catastrophic event that can result in early death or serious hemodynamic dysfunction. The dehydration, immobility, and infections occurring in acute stroke patients puts these patients at risk of developing deep vein thrombosis and pulmonary embolism. Recombinant tissue-type plasminogen activator (rt-PA) is the established therapy for acute ischemic stroke, and its prompt administration results in a better outcome in stroke patients. We describe a 73-year-old man who arrived at the emergency room within 2 hours of acute onset of left hemiparesis who was treated with rt-PA and suffered a pulmonary embolism 3 days after acute stroke therapy. rt-PA is also a current therapy for pulmonary embolism, but an ischemic stroke in the previous 3 months is an absolute contraindication to thrombolysis because of the high risk of intracranial hemorrhage. We discuss clinical and therapeutic decisions and review the current literature.
Lingua originaleEnglish
pagine (da-a)e667-e667-70
RivistaJournal of Stroke and Cerebrovascular Diseases
Volume22
DOI
Stato di pubblicazionePubblicato - 2013

Keywords

  • Acute stroke
  • deep venous thrombosis
  • heparin
  • pulmonary embolism
  • rt-PA
  • systemic thrombolysis

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