@article{5f21907d1e7140c8bb12fe6828c5b37f,
title = "Psychological profile and unexpected pain in oral lichen planus: A case–control multicenter SIPMO studya",
abstract = "Objectives: To analyze psychological profiles, pain, and oral symptoms in patients with oral lichen planus (OLP). Materials and methods: 300 patients with keratotic OLP (K-OLP; reticular, papular, plaque-like subtypes), 300 patients with predominant non-keratotic OLP (nK-OLP; erythematosus atrophic, erosive, ulcerative, bullous subtypes), and 300 controls were recruited in 15 universities. The number of oral sites involved and oral symptoms were recorded. The Numeric Rating Scale (NRS), Total Pain Rating Index (T-PRI), Hamilton Rating Scales for Depression and for Anxiety (HAM-D and HAM-A), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS) were administered. Results: The OLP patients, especially the nK-OLP, showed higher scores in the NRS, T-PRI, HAM-D, HAM-A and PSQI compared with the controls (p-value <.001**). A positive correlation between the NRS, T-PRI, HAM-A, HAM-D, and PSQI was found with the number of oral symptoms and number of oral sites involved. Pain was reported in 67.3% of nK-OLP and 49.7% of K-OLP cases with poor correspondence between the site of lesions and the site of the symptoms. Conclusions: Mood disorders are frequently associated with OLP with an unexpected symptomatology correlated with the number of oral symptoms and with the extension of disease suggesting a peripheral neuropathy.",
keywords = "anxiety, depression, oral lichen planus, pain, sleep disturbance, anxiety, depression, oral lichen planus, pain, sleep disturbance",
author = "Daniela Adamo and Elena Calabria and Noemi Coppola and {Lo Muzio}, Lorenzo and Michele Giuliani and Bizzoca, {Maria Eleonora} and Lorenzo Azzi and Fabio Croveri and Giuseppe Colella and Boschetti, {Ciro Emiliano} and Lucio Montebugnoli and Davide Gissi and Mario Gabriele and Marco Nisi and Andrea Sardella and Giovanni Lodi and Varoni, {Elena M.} and Amerigo Giudice and Alessandro Antonelli and Marco Cabras and Alessio Gambino and Paolo Vescovi and Alessandra Majorana and Elena Bardellini and Giuseppina Campisi and Vera Panzarella and Spadari Francesco and Sonia Marino and Monica Pentenero and Marco Ardore and Matteo Biasotto and Margherita Gobbo and {Guarda Nardini}, Luca and Umberto Romeo and Gianluca Tenore and Rosario Serpico and Carlo Lajolo and Gioele Gioco and Massimo Aria and Mignogna, {Michele Davide}",
year = "2021",
doi = "10.1111/odi.13787",
language = "English",
volume = "28",
pages = "398--414",
journal = "Oral Diseases",
issn = "1354-523X",
publisher = "-BLACKWELL MUNKSGAARD, 1 ROSENORNS ALLE, FREDERIKSBERG C, DENMARK, DK-1970 -Macmillan Magazines Limited:Porters South Crinian Street, London N1 9XW United Kingdom:011 44 207 8334000, 011 44 171 8434982, Fax: 011 44 207 812358",
}