Proteomics and neonatal infection

Giovanni Vento; Chiara Tirone; Claudia Aurilia; Milena Tana; Andrea Piras; A. Lio; Ghennet Tesfagabir; Massimo Castagnola; Chiara Fanali; Costantino Romagnoli

Proteomics and neonatal infection

Giovanni Vento, Chiara Tirone, Claudia Aurilia, Milena Tana, Andrea Piras, A. Lio, Ghennet Tesfagabir, Massimo Castagnola, Chiara Fanali, Costantino Romagnoli

Risultato della ricerca: Contributo in rivista › Articolo in rivista

Abstract

Antimicrobial peptides plays an important role in the host innate defence network, even in humans. Recent studies demonstrated the capacity of human airways epithelial cells to synthesize antimicrobial peptides, and their multifunctional role in the primary immunity. The presence of ct-defensins in bronchoalveolar lavage fluid (BALF) was investigated in a cohort of preterm newborns with gestational age (GA) < or =30 weeks. BALF samples were analysed by High Performance Liquid Chromatography Electrospray Ionization Mass Spectrometer. Our data show that preterm newborns, also at the lower GA, are able to produce defenses, underlining that their innate defence system is already active before the at-term delivery date.

Titolo tradotto del contributo	[Autom. eng. transl.] Proteomics and neonatal infection
Lingua originale	Italian
pagine (da-a)	47-49
Numero di pagine	3
Rivista	Minerva Pediatrica
Volume	2010
Stato di pubblicazione	Pubblicato - 2010

Keywords

. Proteomics and neonatal infection

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abstract = "Antimicrobial peptides plays an important role in the host innate defence network, even in humans. Recent studies demonstrated the capacity of human airways epithelial cells to synthesize antimicrobial peptides, and their multifunctional role in the primary immunity. The presence of ct-defensins in bronchoalveolar lavage fluid (BALF) was investigated in a cohort of preterm newborns with gestational age (GA) < or =30 weeks. BALF samples were analysed by High Performance Liquid Chromatography Electrospray Ionization Mass Spectrometer. Our data show that preterm newborns, also at the lower GA, are able to produce defenses, underlining that their innate defence system is already active before the at-term delivery date.",

keywords = ". Proteomics and neonatal infection, . Proteomics and neonatal infection",

author = "Giovanni Vento and Chiara Tirone and Claudia Aurilia and Milena Tana and Andrea Piras and A. Lio and Ghennet Tesfagabir and Massimo Castagnola and Chiara Fanali and Costantino Romagnoli",

year = "2010",

language = "Italian",

volume = "2010",

pages = "47--49",

journal = "Policlinico infantile",

issn = "0026-4946",

publisher = "Edizioni Minerva Medica:Corso Bramante 83-85, 10126 Turin Italy:011 39 011 678282318, EMAIL: journals.dept@minervamedica.it, INTERNET: http://www.minervamedica.it, Fax: 011 39 011 674502",

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TY - JOUR

T1 - Proteomics and neonatal infection

AU - Vento, Giovanni

AU - Tirone, Chiara

AU - Aurilia, Claudia

AU - Tana, Milena

AU - Piras, Andrea

AU - Lio, A.

AU - Tesfagabir, Ghennet

AU - Castagnola, Massimo

AU - Fanali, Chiara

AU - Romagnoli, Costantino

PY - 2010

Y1 - 2010

N2 - Antimicrobial peptides plays an important role in the host innate defence network, even in humans. Recent studies demonstrated the capacity of human airways epithelial cells to synthesize antimicrobial peptides, and their multifunctional role in the primary immunity. The presence of ct-defensins in bronchoalveolar lavage fluid (BALF) was investigated in a cohort of preterm newborns with gestational age (GA) < or =30 weeks. BALF samples were analysed by High Performance Liquid Chromatography Electrospray Ionization Mass Spectrometer. Our data show that preterm newborns, also at the lower GA, are able to produce defenses, underlining that their innate defence system is already active before the at-term delivery date.

AB - Antimicrobial peptides plays an important role in the host innate defence network, even in humans. Recent studies demonstrated the capacity of human airways epithelial cells to synthesize antimicrobial peptides, and their multifunctional role in the primary immunity. The presence of ct-defensins in bronchoalveolar lavage fluid (BALF) was investigated in a cohort of preterm newborns with gestational age (GA) < or =30 weeks. BALF samples were analysed by High Performance Liquid Chromatography Electrospray Ionization Mass Spectrometer. Our data show that preterm newborns, also at the lower GA, are able to produce defenses, underlining that their innate defence system is already active before the at-term delivery date.

KW - . Proteomics and neonatal infection

UR - http://hdl.handle.net/10807/23072

M3 - Articolo in rivista

SN - 0026-4946

VL - 2010

SP - 47

EP - 49

JO - Policlinico infantile

JF - Policlinico infantile

ER -

Proteomics and neonatal infection

Abstract

Keywords

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