Pros and Cons of Cryopreserving Allogeneic Stem Cell Products

Caterina Giovanna Valentini, Claudio Pellegrino, Luciana Teofili

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

The COVID-19 pandemic has precipitously changed the practice of transplanting fresh allografts. The safety measures adopted during the pandemic prompted the near-universal graft cryopreservation. However, the influence of cryopreserving allogeneic grafts on long-term transplant outcomes has emerged only in the most recent literature. In this review, the basic principles of cell cryopreservation are revised and the effects of cryopreservation on the different graft components are carefully reexamined. Finally, a literature revision on studies comparing transplant outcomes in patients receiving cryopreserved and fresh grafts is illustrated.
Lingua originaleEnglish
pagine (da-a)N/A-N/A
RivistaCells
Volume13
DOI
Stato di pubblicazionePubblicato - 2024

Keywords

  • COVID-19
  • allogeneic hematopoietic stem cell transplant
  • cryopreservation

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