TY - JOUR
T1 - Probiotics and health: An evidence-based review
AU - Aureli, Paolo
AU - Capurso, Lucio
AU - Castellazzi, Anna Maria
AU - Clerici, Mario
AU - Giovannini, Marcello
AU - Morelli, Lorenzo
AU - Poli, Andrea
AU - Pregliasco, Fabrizio Ernesto
AU - Salvini, Filippo
AU - Zuccotti, Gian Vincenzo
PY - 2011
Y1 - 2011
N2 - The intestinal microbiota is an ecosystem formed by a variety of ecological niches, made of several bacterial
species and a very large amount of strains. The microbiota is in close contact with the intestinal
mucosa or epithelial interface which is, after the respiratory area, the largest surface of the body, occupying
approximately 250–400m2. The physiological activities of the microbiota are manifold and are just
being unraveled. Based on the observations of the multiple roles played by the microbiota in health and
disease, the notion of modifying it with appropriate formulations, i.e. probiotics, is being tested in several
settings.
This review summarizes the current knowledge on probiotics and discusses both limitations and
acquired evidence to support their use in preventive and therapeutic medicine.
AB - The intestinal microbiota is an ecosystem formed by a variety of ecological niches, made of several bacterial
species and a very large amount of strains. The microbiota is in close contact with the intestinal
mucosa or epithelial interface which is, after the respiratory area, the largest surface of the body, occupying
approximately 250–400m2. The physiological activities of the microbiota are manifold and are just
being unraveled. Based on the observations of the multiple roles played by the microbiota in health and
disease, the notion of modifying it with appropriate formulations, i.e. probiotics, is being tested in several
settings.
This review summarizes the current knowledge on probiotics and discusses both limitations and
acquired evidence to support their use in preventive and therapeutic medicine.
KW - Immune system
KW - Microbiota
KW - Probiotics
KW - Immune system
KW - Microbiota
KW - Probiotics
UR - http://hdl.handle.net/10807/6573
M3 - Article
SN - 1043-6618
SP - 366
EP - 376
JO - Pharmacological Research
JF - Pharmacological Research
ER -