Probiotics and health: An evidence-based review

Paolo Aureli, Lucio Capurso, Anna Maria Castellazzi, Mario Clerici, Marcello Giovannini, Lorenzo Morelli, Andrea Poli, Fabrizio Ernesto Pregliasco, Filippo Salvini, Gian Vincenzo Zuccotti

Risultato della ricerca: Contributo in rivistaArticolo in rivista

176 Citazioni (Scopus)


The intestinal microbiota is an ecosystem formed by a variety of ecological niches, made of several bacterial species and a very large amount of strains. The microbiota is in close contact with the intestinal mucosa or epithelial interface which is, after the respiratory area, the largest surface of the body, occupying approximately 250–400m2. The physiological activities of the microbiota are manifold and are just being unraveled. Based on the observations of the multiple roles played by the microbiota in health and disease, the notion of modifying it with appropriate formulations, i.e. probiotics, is being tested in several settings. This review summarizes the current knowledge on probiotics and discusses both limitations and acquired evidence to support their use in preventive and therapeutic medicine.
Lingua originaleEnglish
pagine (da-a)366-376
Numero di pagine11
RivistaPharmacological Research
Stato di pubblicazionePubblicato - 2011


  • Immune system
  • Microbiota
  • Probiotics


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