TY - JOUR
T1 - Priorities for health economic methodological research: Results of an expert consultation
AU - Tordrup, David
AU - Chouaid, Christos
AU - Cuijpers, Pim
AU - Dab, William
AU - Van Dongen, Johanna Maria
AU - Espin, Jaime
AU - Jönsson, Bengt
AU - Léonard, Christian
AU - Mcdaid, David
AU - Mckee, Martin
AU - Miguel, José Pereira
AU - Patel, Anita
AU - Reginster, Jean-Yves
AU - Ricciardi, Walter
AU - Rutten-Van Molken, Maureen
AU - Rupel, Valentina Prevolnik
AU - Sach, Tracey
AU - Sassi, Franco
AU - Waugh, Norman
AU - Bertollini, Roberto
PY - 2017
Y1 - 2017
N2 - Background: The importance of economic evaluation in decision making is growing with increasing budgetary pressures on health systems. Diverse economic evidence is available for a range of interventions across national contexts within Europe, but little attention has been given to identifying evidence gaps that, if filled, could contribute to more efficient allocation of resources. One objective of the Research Agenda for Health Economic Evaluation project is to determine the most important methodological evidence gaps for the ten highest burden conditions in the European Union (EU), and to suggest ways of filling these gaps. Methods: The highest burden conditions in the EU by Disability Adjusted Life Years were determined using the Global Burden of Disease study. Clinical interventions were identified for each condition based on published guidelines, and economic evaluations indexed in MEDLINE were mapped to each intervention. A panel of public health and health economics experts discussed the evidence during a workshop and identified evidence gaps. Results: The literature analysis contributed to identifying cross-cutting methodological and technical issues, which were considered by the expert panel to derive methodological research priorities. Conclusions: The panel suggests a research agenda for health economics which incorporates the use of real-world evidence in the assessment of new and existing interventions; increased understanding of cost-effectiveness according to patient characteristics beyond the -omics approach to inform both investment and disinvestment decisions; methods for assessment of complex interventions; improved cross-talk between economic evaluations from health and other sectors; early health technology assessment; and standardized, transferable approaches to economic modeling.
AB - Background: The importance of economic evaluation in decision making is growing with increasing budgetary pressures on health systems. Diverse economic evidence is available for a range of interventions across national contexts within Europe, but little attention has been given to identifying evidence gaps that, if filled, could contribute to more efficient allocation of resources. One objective of the Research Agenda for Health Economic Evaluation project is to determine the most important methodological evidence gaps for the ten highest burden conditions in the European Union (EU), and to suggest ways of filling these gaps. Methods: The highest burden conditions in the EU by Disability Adjusted Life Years were determined using the Global Burden of Disease study. Clinical interventions were identified for each condition based on published guidelines, and economic evaluations indexed in MEDLINE were mapped to each intervention. A panel of public health and health economics experts discussed the evidence during a workshop and identified evidence gaps. Results: The literature analysis contributed to identifying cross-cutting methodological and technical issues, which were considered by the expert panel to derive methodological research priorities. Conclusions: The panel suggests a research agenda for health economics which incorporates the use of real-world evidence in the assessment of new and existing interventions; increased understanding of cost-effectiveness according to patient characteristics beyond the -omics approach to inform both investment and disinvestment decisions; methods for assessment of complex interventions; improved cross-talk between economic evaluations from health and other sectors; early health technology assessment; and standardized, transferable approaches to economic modeling.
KW - Cost-effectiveness analysis
KW - Economic evaluation
KW - Expert opinion
KW - Health Policy
KW - Cost-effectiveness analysis
KW - Economic evaluation
KW - Expert opinion
KW - Health Policy
UR - http://hdl.handle.net/10807/124666
UR - http://journals.cambridge.org/action/displayjournal?jid=thc
U2 - 10.1017/S0266462317000666
DO - 10.1017/S0266462317000666
M3 - Article
SN - 0266-4623
VL - 33
SP - 609
EP - 619
JO - International Journal of Technology Assessment in Health Care
JF - International Journal of Technology Assessment in Health Care
ER -