Primary multifocal lymphoma of peripheral nervous system: Case report and review of the literature

Mario Sabatelli, Vittoria Rufini, Simona Gaudino, Stefan Hohaus, Antonella Coli, Alessandra Del Grande, Marco Luigetti, Amelia Conte, Giuseppe Granata, Annemilia Del Ciello, Eduardo Marcos Fernandez Marquez, Libero Lauriola

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

19 Citazioni (Scopus)

Abstract

Introduction: Primary lymphomas of peripheral nerves are extremely rare, and only a few cases have been reported. Methods: We describe the clinical, neurophysiological, radiological, and pathological findings in a 61-year-old woman affected by primary multifocal lymphoma of the peripheral nervous system without systemic involvement. Results: Fascicular left femoral nerve biopsy was decisive for the diagnosis of diffuse large B-cell non-Hodgkin lymphoma. Magnetic resonance imaging, fluorine-18 fluorodeoxyglucose positron emission tomography computed tomography, and nerve ultrasound contributed to the diagnosis. Conclusions: Primary lymphoma of peripheral nerves (PLPNs) is a rare but potentially treatable condition, which is frequently misdiagnosed. In the literature, there are very few descriptions of PLPNs, most of which are mononeuropathies. The possibility of a neuropathy associated with lymphoma should be considered in patients with poor response to treatment and severe pain symptoms. Muscle Nerve, 2014.
Lingua originaleEnglish
pagine (da-a)1016-1022
Numero di pagine7
RivistaMUSCLE & NERVE
Volume50
DOI
Stato di pubblicazionePubblicato - 2014

Keywords

  • FDG PET-CT
  • nerve biopsy
  • nerve ultrasound
  • neurolymphomatosis
  • primary lymphoma of peripheral nerves

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