Prevalence of primary clarithromycin resistance in Helicobacter pylori strains over a 15 year period in Italy

Cesare Hassan, V De Francesco, M Margiotta, A Zullo, F Giorgio, O Burattini, G Stoppino, U Cea, A Pace, M Zotti, S Morini, C Panella, E. Ierardi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

86 Citazioni (Scopus)

Abstract

The frequency of primary clarithromycin resistance in Helicobacter pylori strains is increasing worldwide, and its presence significantly reduces the treatment efficacy of infection. This study aimed to evaluate whether the progression of the prevalence of clarithromycin resistance over a 15 year period has increased and whether a possible change in the distribution of the three most frequent point mutations, which account for the large majority of clarithromycin resistance cases, has taken place.
Lingua originaleEnglish
pagine (da-a)783-785
Numero di pagine3
RivistaJournal of Antimicrobial Chemotherapy
Volume59
DOI
Stato di pubblicazionePubblicato - 2007
Pubblicato esternamente

Keywords

  • Anti-Bacterial Agents
  • Clarithromycin
  • Drug Resistance, Bacterial
  • Female
  • Helicobacter Infections
  • Helicobacter pylori
  • Humans
  • Italy
  • Male
  • Microbial Sensitivity Tests
  • Point Mutation
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sex Characteristics

Fingerprint

Entra nei temi di ricerca di 'Prevalence of primary clarithromycin resistance in Helicobacter pylori strains over a 15 year period in Italy'. Insieme formano una fingerprint unica.

Cita questo