TY - JOUR
T1 - Prevalence and associated variables of postdialysis fatigue: results of a prospective multicenter study
AU - Bossola, Maurizio
AU - Marzetti, Emanuele
AU - Di Stasio, Enrico
AU - Vulpio, Carlo
PY - 2017
Y1 - 2017
N2 - AIMS:
Little is known about postdialysis fatigue (PDF), a debilitating symptom of hemodialysis patients.
METHODS:
In 5 hemodialysis units of northern-centre Italy, patients were regarded to suffer from PDF if they spontaneously offered this complaint when asked the open-ended question: Do you feel better or worse after dialysis? If worse, please specify in which way. A complaint of fatigue would be probed further with questions directed at its duration, frequency and intensity, allowing creation of a fatigue index of severity (one third of the sum of these three parameters, each rated from 1 to 5). Patients were stratified into three groups according the severity of PDF: 1) score = 0; 2) score = 1-3; 3) score > 3.
RESULTS:
We studied 271 patients: 164 had PDF and 107 had not. PDF patients had significantly longer time of recovery after dialysis (TIRD). TIRD was significantly associated with PDF duration, intensity, and frequency. Patients with PDF were older and had a lower ADL score. At multivariate analysis, PDF was significantly associated with TIRD. In multivariate model that did not include TIRD, PDF was independently associated with age and ADL. Sixty patients had moderate PDF and 104 severe PDF. In patients with severe PDF, age and dialytic age were higher, ADL and IADL scores were lower, TIRD was longer and the ultrafiltration rate was lower. At multivariate analysis, PDF severity was independently associated with TIRD. In the model without TIRD, PDF severity was associated with ADL only.
CONCLUSION:
PDF is frequent and associated with age and ADL. Dialytic variables seem unrelated to PDF.
AB - AIMS:
Little is known about postdialysis fatigue (PDF), a debilitating symptom of hemodialysis patients.
METHODS:
In 5 hemodialysis units of northern-centre Italy, patients were regarded to suffer from PDF if they spontaneously offered this complaint when asked the open-ended question: Do you feel better or worse after dialysis? If worse, please specify in which way. A complaint of fatigue would be probed further with questions directed at its duration, frequency and intensity, allowing creation of a fatigue index of severity (one third of the sum of these three parameters, each rated from 1 to 5). Patients were stratified into three groups according the severity of PDF: 1) score = 0; 2) score = 1-3; 3) score > 3.
RESULTS:
We studied 271 patients: 164 had PDF and 107 had not. PDF patients had significantly longer time of recovery after dialysis (TIRD). TIRD was significantly associated with PDF duration, intensity, and frequency. Patients with PDF were older and had a lower ADL score. At multivariate analysis, PDF was significantly associated with TIRD. In multivariate model that did not include TIRD, PDF was independently associated with age and ADL. Sixty patients had moderate PDF and 104 severe PDF. In patients with severe PDF, age and dialytic age were higher, ADL and IADL scores were lower, TIRD was longer and the ultrafiltration rate was lower. At multivariate analysis, PDF severity was independently associated with TIRD. In the model without TIRD, PDF severity was associated with ADL only.
CONCLUSION:
PDF is frequent and associated with age and ADL. Dialytic variables seem unrelated to PDF.
KW - activity daily living
KW - fatigue
KW - hemodialysis
KW - postdialysis fatigue
KW - activity daily living
KW - fatigue
KW - hemodialysis
KW - postdialysis fatigue
UR - http://hdl.handle.net/10807/122159
U2 - 10.1111/nep.13059
DO - 10.1111/nep.13059
M3 - Article
SN - 1320-5358
SP - 1
EP - 10
JO - Nephrology
JF - Nephrology
ER -