Presentation and Validation of the Multiple Sclerosis Depression Rating Scale: A Test Specifically Devised to Investigate Affective Disorders in Multiple Sclerosis Patients

Camillo Marra, Guido Gainotti, Davide Quaranta, Massimiliano Zinno, Agata Katia Patanella, Chiara Piccininni, Anna Paola Batocchi, Mj Messina

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

Abstract

Accurate diagnosis of depression in patients affected by MS is important, as it may be a cause of reduced quality of life and increased suicide risk. We present a new scale, the Multiple Sclerosis Depression Rating Scale (MSDRS), and assess its diagnostic accuracy in comparison to the Beck Depression Inventory (BDI). A total of 94 MS participants were classified as non-depressed (N = 44) or affected by mood disorder associated to MS with depressive manifestations (MSD-MDDM; N = 37) or with a major depression-like episode (MSD-MDL; N = 13). Each participant underwent a psychiatric interview, MSDRS, and BDI; diagnostic accuracy was evaluated using area under the ROC curve (AROC). The diagnostic accuracy of MSDRS and BDI was comparable when diagnosing both MSD-MDDM and MSD-MDL (AROC respectively 0.8998 and 0.8659); the MSDRS showed higher accuracy for the diagnosis of MSD-MDL (AROC respectively 0.9278 and 0.8314; p = .038). The MSDRS may be a reliable tool for the diagnosis of depression in MS.
Lingua originaleEnglish
pagine (da-a)571-587
Numero di pagine17
RivistaNEUROPSYCHOLOGY, DEVELOPMENT, AND COGNITION.
Volume2012
Stato di pubblicazionePubblicato - 2012

Keywords

  • Multiple sclerosis

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