Presentation and Validation of the Multiple Sclerosis Depression Rating Scale: A Test Specifically Devised to Investigate Affective Disorders in Multiple Sclerosis Patients

Davide Quaranta, Camillo Marra, Massimiliano Zinno, Agata Katia Patanella, Chiara Piccininni, Anna Paola Batocchi, Guido Gainotti, 33184, DI MEDICINA E CHIRURGIA "A.GEMELLI" FACOLTA', ROMA - Dipartimento di Neuroscienze, DI PSICOLOGIA FACOLTA', DI MEDICINA E CHIRURGIA "A.GEMELLI" FACOLTA', DI PSICOLOGIA FACOLTA', DI MEDICINA E CHIRURGIA "A.GEMELLI" FACOLTA', Mj Messina, DI PSICOLOGIA FACOLTA'

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

Abstract

Accurate diagnosis of depression in patients affected by MS is important, as it may be a cause of reduced quality of life and increased suicide risk. We present a new scale, the Multiple Sclerosis Depression Rating Scale (MSDRS), and assess its diagnostic accuracy in comparison to the Beck Depression Inventory (BDI). A total of 94 MS participants were classified as non-depressed (N = 44) or affected by mood disorder associated to MS with depressive manifestations (MSD-MDDM; N = 37) or with a major depression-like episode (MSD-MDL; N = 13). Each participant underwent a psychiatric interview, MSDRS, and BDI; diagnostic accuracy was evaluated using area under the ROC curve (AROC). The diagnostic accuracy of MSDRS and BDI was comparable when diagnosing both MSD-MDDM and MSD-MDL (AROC respectively 0.8998 and 0.8659); the MSDRS showed higher accuracy for the diagnosis of MSD-MDL (AROC respectively 0.9278 and 0.8314; p = .038). The MSDRS may be a reliable tool for the diagnosis of depression in MS.
Lingua originaleEnglish
pagine (da-a)571-587
Numero di pagine17
RivistaNEUROPSYCHOLOGY, DEVELOPMENT, AND COGNITION.
Volume2012
Stato di pubblicazionePubblicato - 2012

Keywords

  • Multiple sclerosis

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