Potential role for retinoic acid in patients with Cushing's disease

Salvatore Maria Corsello, Alfredo Pontecorvi, F Pecori Giraldi, Ag Ambrogio, M Andrioli, F Sanguin, I Karamouzis, C Scaroni, E Arvat, F. Cavagnini

Risultato della ricerca: Contributo in rivistaArticolo in rivista

88 Citazioni (Scopus)

Abstract

Cushing's disease, i.e. cortisol excess due to an ACTH-secreting pituitary adenoma, is a rare disorder with considerable morbidity and mortality but no satisfactory medical treatment as yet. Experimental data have recently shown that retinoic acid restrains ACTH secretion by tumoral corticotropes.
Lingua originaleEnglish
pagine (da-a)3577-3583
Numero di pagine7
RivistaTHE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Volume97
DOI
Stato di pubblicazionePubblicato - 2012

Keywords

  • ACTH-Secreting Pituitary Adenoma
  • Adenoma
  • Adolescent
  • Adrenocorticotropic Hormone
  • Adult
  • Antineoplastic Agents
  • Female
  • Humans
  • Hydrocortisone
  • Male
  • Middle Aged
  • Pituitary ACTH Hypersecretion
  • Prospective Studies
  • Treatment Outcome
  • Tretinoin
  • Young Adult

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