Abstract
Possible sources of iron for lipid peroxidation are described and discussed. In particular. evidence is presented that microsomes contain ferric nonheme iron which may participate in formation of lipid oxidants. provided reductants are available to favor its mobilization from membrane binding sites. Aging-and tumor-associated changes of this microsomal pool of nonheme iron are also described and discussed from biochemical and biomedical viewpoints. © 1991 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
| Lingua originale | English |
|---|---|
| pagine (da-a) | 99-106 |
| Numero di pagine | 8 |
| Rivista | Free Radical Research |
| Volume | 12 |
| DOI | |
| Stato di pubblicazione | Pubblicato - 1991 |
Keywords
- Aging
- Ferritin
- Iron
- Lipid peroxidation
- Nonheme-nonferritin iron
- Tumors