Population structure in the Mediterranean basin: A Y chromosome perspective

Vincenzo Lorenzo Pascali, Cristian Capelli, N Redhead, V Romano, F Calì, G Lefranc, V Delague, A Megarbane, A Felice, P. I. Neophytou, Z. Poulli, A. Novelletto, P. Malaspina, L. Terrenato, A. Berebbi, M. Fellous, M. G. Thomas, D. B. Goldstein

Risultato della ricerca: Contributo in rivistaArticolo in rivista

53 Citazioni (Scopus)

Abstract

The Mediterranean region has been characterised by a number of pre-historical and historical demographic events whose legacy on the current genetic landscape is still a matter of debate. In order to investigate the degree of population structure across the Mediterranean, we have investigated Y chromosome variation in a large dataset of Mediterranean populations, 11 of which are first described here. Our analyses identify four main clusters in the Mediterranean that can be labelled as North Africa, Arab, Central-East and West Mediterranean. In particular, Near Eastern samples tend to separate according to the presence of Arab Y chromosome lineages, suggesting that the Arab expansion played a major role in shaping the current genetic structuring within the Fertile Crescent. © University College London 2005.
Lingua originaleEnglish
pagine (da-a)207-225
Numero di pagine19
RivistaAnnals of Human Genetics
Volume70
DOI
Stato di pubblicazionePubblicato - 2006

Keywords

  • Arab
  • Ethnic Groups
  • Genetics, Population
  • Humans
  • Male
  • Mediterranean Region
  • North Africa
  • Southern Europe
  • Variation (Genetics)
  • Y chromosome, Chromosomes, Human, Y
  • article
  • cluster analysis
  • demography
  • gene locus
  • genetic linkage
  • genetic variability
  • genotype
  • haplotype
  • human
  • male
  • population genetics
  • population structure
  • priority journal

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