TY - JOUR
T1 - Polyunsaturated Fatty Acids as Prebiotics: Innovation or Confirmation?
AU - Rinninella, Emanuele
AU - Costantini, Lara
PY - 2022
Y1 - 2022
N2 - The International Scientific Association for Probiotics and Prebiotics (ISAPP), in its last consensus statement about prebiotics, defined polyunsaturated fatty acids (PUFAs) as "candidate prebiotics" due to a lack of complete scientific evidence. Previous studies have demonstrated the ability of microbiota to metabolize PUFAs, although the role of the resulting metabolites in the host is less known. Recent partial evidence shows that these metabolites can have important health effects in the host, reinforcing the concept of the prebiotic action of PUFAs, despite the data being mostly related to omega-6 linoleic acid and to lactobacilli taxon. However, considering that the symbionts in our gut benefit from the nutritional molecules that we include in our diet, and that bacteria, like all living organisms, cannot benefit from a single nutritional molecule, the concept of the "correct prebiotic diet" should be the new frontier in the field of gut microbiota research.
AB - The International Scientific Association for Probiotics and Prebiotics (ISAPP), in its last consensus statement about prebiotics, defined polyunsaturated fatty acids (PUFAs) as "candidate prebiotics" due to a lack of complete scientific evidence. Previous studies have demonstrated the ability of microbiota to metabolize PUFAs, although the role of the resulting metabolites in the host is less known. Recent partial evidence shows that these metabolites can have important health effects in the host, reinforcing the concept of the prebiotic action of PUFAs, despite the data being mostly related to omega-6 linoleic acid and to lactobacilli taxon. However, considering that the symbionts in our gut benefit from the nutritional molecules that we include in our diet, and that bacteria, like all living organisms, cannot benefit from a single nutritional molecule, the concept of the "correct prebiotic diet" should be the new frontier in the field of gut microbiota research.
KW - Gut microbiota
KW - Omega 3 fatty acids
KW - Gut microbiota
KW - Omega 3 fatty acids
UR - http://hdl.handle.net/10807/194559
U2 - 10.3390/foods11020146
DO - 10.3390/foods11020146
M3 - Article
SN - 2304-8158
VL - 2022
SP - 1
EP - 6
JO - Foods
JF - Foods
ER -